RAB0385

Atrial Natriuretic Peptide EIA Kit

for serum, plasma, culture supernatant and cell lysates

• Sinónimos: Natriuretic peptides A, Prepronatriodilatin, ANP
• Código UNSPSC: 41116158
• NACRES: NA.32

Propiedades

• reactividad de especies: mouse, human, rat
• envase: kit of 96 wells (12 strips x 8 wells)
• técnicas: ELISA: suitable; enzyme immunoassay: suitable
• entrada: sample type serum; sample type cell lysate; sample type plasma; sample type culture supernatant(s)
• assay range: inter-assay cv: <15%; intra-assay cv: <10%; sensitivity: 1.02 pg/mL; standard curve range: 0.1-1000 pg/mL
• método de detección: colorimetric
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... NPPA(4878)

Descripción

Descripción general

The ANP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting ANP peptide based on the principle of Competitive Enzyme Immunoassay. EIA-ANP-1 targets the common sequence of human, mouse and rat, and thus may be used to detect ANP expression in all these species with high specificity and sensitivity.

Inmunógeno

Atrial Natriuretic Peptide, synthetic peptide

Aplicación

Atrial Natriuretic Peptide EIA Kit has been used for the quantification of atrial natriuretic peptide (ANP) in cell culture.

For research use only. Not for use in diagnostic procedures.
Atrial Natriuretic Peptide EIA Kit has been used to measure ANP levels in diabetes mellitus patients.

Acciones bioquímicas o fisiológicas

Atrial natriuretic peptide (ANP) is a polypeptide hormone released in response to atrial dilation and it stimulates diuresis, natriuresis and vasorelaxation. ANP acts as an inhibitor of renin-angiotensin-aldosterone system (RAAS) pathway. It also has a major role in body fluid homeostasis and maintenance of blood pressure. Binding of ANP to receptors on target cell stimulate the production of cyclic guanosine monophosphate (GMP). Overexpression of ANP leads to congestive heart failure in the human. Experimental studies show that ANP can be used as a therapeutic for stimulating angiogenesis in ischemic tissues. N-terminal ANP prohormone functions as a biomarker for asymptomatic systolic left ventricular (LV) dysfunction, congestive heart failure and cardiovascular mortality.

Los componentes del kit también están disponibles por separado

• RABHRP3 HRP-Streptavidin

Información de seguridad

• Pictogramas: GHS05
• Palabra de señalización: Warning
• Frases de peligro: H290
• Consejos de prudencia: P234 - P390
• Clasificaciones de peligro: Met. Corr. 1
• Código de clase de almacenamiento: 8A - Combustible corrosive hazardous materials