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Merck
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Key Documents

P3558

Sigma-Aldrich

Paraplast®

for tissue embedding

Sinónimos:

Paraffin – polyisobutylene mixture

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About This Item

Número de CAS:
MDL number:
UNSPSC Code:
12171500
NACRES:
NA.47

form

solid

mp

56-57 °C (lit.)
56-57 °C

application(s)

hematology
histology

storage temp.

room temp

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General description

Paraplast® is a paraffin–polyisobutylene mixture for tissue embedding and infiltration. It is a refined combination of highly purified paraffin with plastic polymers. It produces minimal tissue compression and wrinkle-free sections and cuts to 4 μm thickness with excellent ribbon continuity.

Application

Paraplast® has been used for tissue embedding and in the following applications:
  • to screen major groups of vertebrates for the presence of cardiac smooth muscle and its phylogenetic distribution in terrestrial and aquatic turtles
  • to study the relationship between membrane impedance and dendrite length of hippocampal neurons
  • to compare the regenerative properties of human stem cells of the apical papilla as an alternative to other dental stem cells

Features and Benefits

  • Minimal tissue compression.
  • Produces wrinkle-free sections.
  • Excellent ribbon continuity.

Other Notes

Double filtered paraffin wax in pellet form.

Legal Information

Paraplast is a registered trademark of Leica Biosystems

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Diana B Sequeira et al.
Clinical oral investigations, 25(9), 5317-5329 (2021-02-26)
To compare the regenerative properties of human stem cells of the apical papilla (SCAPs) embedded in a platelet-rich plasma (PRP) scaffold, when implanted in vivo using an organotypic model composed of human root segments, with or without the presence of
Jessica N Witchley et al.
Cell host & microbe, 25(3), 432-443 (2019-03-15)
Candida albicans is a gut commensal and opportunistic pathogen. The transition between yeast and invasive hyphae is central to virulence but has unknown functions during commensal growth. In a mouse model of colonization, yeast and hyphae co-occur throughout the gastrointestinal
Positive Effects of Diphlorethohydroxycarmalol (DPHC) on the Stability of the Integument Structure in Diet-Induced Obese Female Mice
Chae-Lim Kim
Development & reproduction (2015)
Intestinal metabolism of weaned piglets fed a typical United States
or European diet with or without supplementation
of tributyrin and lactitol
A. Piva
Journal of Animal Science (2008)
Cristina Barrero et al.
Planta, 229(2), 235-247 (2008-10-03)
Transfer cells have specializations that facilitate the transport of solutes across plant exchange surfaces. ZmMRP-1 is a maize (Zea mays) endosperm transfer cell-specific transcriptional activator that plays a central role in the regulatory pathways controlling transfer cell differentiation and function.

Contenido relacionado

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

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