L0302511

ETT Activator

• Sinónimos: 5-(Ethylthio)-1H-tetrazole, 5-(Ethylthio)tetrazole solution
• MDL number: MFCD00068733
• UNSPSC Code: 12352202
• NACRES: NA.21

Propiedades

• type: for DNA synthesis
• Quality Level: 200
• product line: Proligo Reagents
• packaging: pkg of 4 × 2.5 L L0302511-04
• concentration: 39-43 g/L (titration)
• impurities: ≤30 ppm water content (Karl Fischer)
• color: clear
• SMILES string: CCSc1nnn[nH]1
• InChI: 1S/C3H6N4S/c1-2-8-3-4-6-7-5-3/h2H2,1H3,(H,4,5,6,7)
• InChI key: GONFBOIJNUKKST-UHFFFAOYSA-N

Descripción

General description

ETT activator is an activator solution containing 5-(Ethylthio)-1H-tetrazole – a powerful activator – in acetonitrile. It is mixed with phosphoramidite during the extension step in which it reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.

Application

ETT activator has been used in the fast and low-cost synthesis of photolithographic DNA microarrays.

Información de seguridad

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H302 + H312 + H332,H315,H318
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 35.6 °F
• flash_point_c: 2 °C