G7877

Glucose-6-phosphate Dehydrogenase from baker′s yeast (S. cerevisiae)

Type VII, ammonium sulfate suspension, ≥200 units/mg protein

• Sinónimos: glucose-6-phosphate dehydrogenase (NADP+), G-6-P-DH, Zwischenferment
• Número de CAS: 9001-40-5
• Comisión internacional de enzimas: 1.1.1.49 (BRENDA, IUBMB)
• Número CE: 232-602-6
• Número MDL: MFCD00081656
• Código UNSPSC: 12352204
• NACRES: NA.54

Propiedades

• origen biológico: bakers yeast
• Nivel de calidad: 200
• tpo: Type VII
• Formulario: ammonium sulfate suspension
• actividad específica: ≥200 units/mg protein
• mol peso: 128 kDa
• técnicas: cell based assay: suitable
• solubilidad: water: soluble
• aplicaciones: diagnostic assay manufacturing
• temp. de almacenamiento: 2-8°C
• Información sobre el gen: Saccharomyces cerevisiae ... ZWF1(855480)

Descripción

Descripción general

Glucose 6-phosphate dehydrogenase (G-6-P-DH) is a key regulatory enzyme in the first step of the pentose phosphate pathway.[1] G-6-P-DH is a glycoprotein with a molecular mass of 128 kDa (gel filtration).[2]

Aplicación

Glucose-6-phosphate dehydrogenase has been used in a study to investigate the effect of dehydroepiandrosterone on cell growth and mitochondrial function in TM-3 cells. Glucose-6-phosphate dehydrogenase has also been used in a study to investigate the incidence of apoptosis and transcript abundance in bovine follicular cells. Glucose-6-phosphate dehydrogenase is used to test ketose reductase activity in developing maize endosperm.[3]

Acciones bioquímicas o fisiológicas

Glucose-6-phosphate dehydrogenase catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconolacetone as the first step in the pentose phosphate pathway.

Definición de unidad

One unit will oxidize 1.0 μmole of D-glucose 6-phosphate to 6-phospho-D-gluconate per min in the presence of NADP at pH 7.4 at 25 °C.

Forma física

Crystalline suspension in 3.2 M (NH₄)₂SO₄ solution, pH 7.0

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H334
• Consejos de prudencia: P261 - P284 - P501
• Clasificaciones de peligro: Resp. Sens. 1
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)