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Key Documents

F5551

Sigma-Aldrich

Hemagglutinin, Filamentous

from Bordetella pertussis, lyophilized powder

Sinónimos:

Anti-HA, FHA, Hemagglutinin, Fimbrial

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About This Item

MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

product name

Hemagglutinin, Filamentous from Bordetella pertussis, lyophilized powder

form

lyophilized powder

Quality Level

mol wt

200-220 kDa

shipped in

wet ice

storage temp.

2-8°C

General description

Filamentous Hemagglutinin (FHA) from Bordetella pertussis is a major virulence-associated adhesion factor secreted by these bacteria. It contains an arginine-glycine-aspartate (RGD) sequence. FHA is a derivative of its precursor FhaB.

Biochem/physiol Actions

Filamentous Hemagglutinin (FHA) from Bordetella pertussis enables the attachment of bacteria to the epithelium of the upper respiratory tract. The arginine-glycine-aspartate (RGD) sequence mediates the binding of FHA to sulfated polysaccharides and pulmonary macrophage integrins.

Physical form

lyophilized from 0.05 M Tris HCL, pH 8, with 0.5 M sodium chloride and 5% sucrose

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Louise De Weerdt et al.
Frontiers in immunology, 15, 1360201-1360201 (2024-03-11)
Tetanus, diphtheria, acellular pertussis (Tdap) vaccination is recommended to be administered in every pregnancy. Although the safety of this strategy has been confirmed, the immunogenicity of Tdap vaccination in two successive pregnancies has not yet been described. This study investigated
Elizabeth M Goebel et al.
PloS one, 4(8), e6778-e6778 (2009-08-27)
Although B. bronchiseptica efficiently infects a wide range of mammalian hosts and efficiently spreads among them, it is rarely observed in humans. In contrast to the many other hosts of B. bronchiseptica, humans are host to the apparently specialized pathogen

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