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C7397

Sigma-Aldrich

Cyclophosphamide monohydrate

ISOPAC®

Sinónimos:

2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan

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About This Item

Fórmula empírica (notación de Hill):
C7H15Cl2N2O2P · H2O
Número de CAS:
6055-19-2
Peso molecular:
279.10
Beilstein:
4678992
Número CE:
200-015-4
Número MDL:
MFCD00149395
Código UNSPSC:
51112507
ID de la sustancia en PubChem:
24892961
NACRES:
NA.25

Ensayo

97.0-103.0% (HPLC)

Formulario

powder

mp

49-51 °C (lit.)

temp. de almacenamiento

2-8°C

cadena SMILES

[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

Clave InChI

PWOQRKCAHTVFLB-UHFFFAOYSA-N

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Aplicación

Cyclophosphamide, a nitrogen mustard DNA alkylating agent, is used to study its mechanisms of action as an anticancer and antiimmunity drug.

Acciones bioquímicas o fisiológicas

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.
Cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations.

Envase

Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.

Precaución

Injecting a compatible solvent directly into the vial permits preparation of any desired strength solution without exposure.

Reconstitución

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Información legal

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

ISOPAC de

Referencia del producto
Descripción
Precios

C0768

Cyclophosphamide monohydrate, bulk package

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palabra de señalización

Danger

Frases de peligro

H301,H340,H350,H360FD

Clasificaciones de peligro

Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
MKCW3975
MKCR5119
MKCS5505
MKCL2547
MKCN3646

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