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Merck
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Key Documents

C7278

Sigma-Aldrich

Caseinoglycopeptide from bovine casein

essentially salt-free, lyophilized powder

Sinónimos:

Bovine Casein Glycopeptide

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About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.26

form

essentially salt-free, lyophilized powder

mol wt

~7000

technique(s)

affinity chromatography: suitable

color

white

UniProt accession no.

storage temp.

2-8°C

Gene Information

Amino Acid Sequence

Met-Ala-Ile-Pro-Pro-Lys-Lys-Asn-Gln-Asp-Lys

Application


  • Bioactive Peptide in Dairy Research: Investigation into the effects of bovine caseinoglycopeptide on CD4+ T cells showcased its potential to modulate immune responses, highlighting its application in nutrition and functional food development (Otani et al., 1996).

Biochem/physiol Actions

The soluble carboxyl-terminal moiety of κ-casein. This antithrombotic peptide binds to glycoprotein GPIb in the platelet membrane, thus inhibiting platelet aggregation by blocking the binding of von Willebrand factor.

Preparation Note

Prepared by a modification of the method of Alais and Jolles.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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[Comparative study of the caseinoglycopeptides formed by the action of rennin on caseins from the cow, sheep and goat. II. Study of the non-peptide portion].
C ALAIS et al.
Biochimica et biophysica acta, 51, 315-322 (1961-08-05)
Franz-Georg Hanisch
Analytical chemistry, 83(12), 4829-4837 (2011-04-30)
The sites of mucin-type O-glycosylation are largely unpredictable, making structural analysis by mass spectrometry (MS) indispensible. On the peptide level, a site localization and characterization of O-linked glycans in situ using tandem MS with electron-transfer dissociation or matrix-assisted laser desorption
K Benschop et al.
Journal of clinical microbiology, 46(12), 3965-3970 (2008-10-24)
Human parechoviruses (HPeV) are widespread pathogens belonging to the Picornavirus family. Six genotypes, which have predominantly been isolated from children, are known. Data on prevalence of HPeV genotypes are generally based on cell culture, which may underestimate the prevalence of

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