C3809

Ceftazidime hydrate

90.0-105.0%, contains ~10% sodium carbonate as stabilizer

• Sinónimos: 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinum
• Fórmula empírica (notación de Hill): C₂₂H₂₂N₆O₇S₂ · xH₂O
• Número de CAS: 120618-65-7
• Peso molecular: 546.58 (anhydrous basis)
• Número MDL: MFCD00153936
• Código UNSPSC: 51284108
• ID de la sustancia en PubChem: 24892644
• NACRES: NA.85

Propiedades

• Ensayo: 90.0-105.0%
• Formulario: powder or crystals
• contiene: ~10% sodium carbonate as stabilizer
• espectro de actividad antibiótica: Gram-negative bacteria; Gram-positive bacteria
• Modo de acción: cell wall synthesis | interferes
• temp. de almacenamiento: 2-8°C
• cadena SMILES: [H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].CC(C)(O\N=C(/C(=O)N[C@H]1[C@H]2SCC(C[n+]3ccccc3)=C(N2C1=O)C([O-])=O)c4csc(N)n4)C(O)=O
• InChI: 1S/C22H22N6O7S2.5H2O/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27;;;;;/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34);5*1H2/b26-13-;;;;;/t14-,18-;;;;;/m1...../s1
• Clave InChI: NMVPEQXCMGEDNH-TZVUEUGBSA-N

Descripción

Descripción general

Broad spectrum antibiotic; third generation cephalosporin

Chemical structure: ß-lactam

Aplicación

Ceftazidime hydrate is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis. It is also used in bacterial susceptibility studies and to select mutant colonies of interest.

Used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis.

Acciones bioquímicas o fisiológicas

Cephalosporins, such as ceftazidime , disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.

Otras notas

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H317,H319,H334
• Consejos de prudencia: P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Resp. Sens. 1 - Skin Sens. 1
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Faceshields, Gloves