C1240

Chlormethiazole hydrochloride

≥98% (HPLC), powder

• Sinónimos: 4-methyl-5-(β-chloroethyl)thiazole hydrochloride, 5-(2-Chloroethyl)-4-methylthiazole hydrochloride, Clomethiazole hydrochloride, Somnevrin hydrochloride
• Fórmula empírica (notación de Hill): C₆H₈ClNS · HCl
• Número de CAS: 6001-74-7
• Peso molecular: 198.11
• MDL number: MFCD00673948
• UNSPSC Code: 12352200
• PubChem Substance ID: 329774745
• NACRES: NA.77

Propiedades

• description: Store desiccated
• assay: ≥98% (HPLC)
• form: powder
• color: off-white
• solubility: H₂O: soluble >10 mg/mL
• originator: AstraZeneca
• SMILES string: Cl.Cc1ncsc1CCCl
• InChI: 1S/C6H8ClNS.ClH/c1-5-6(2-3-7)9-4-8-5;/h4H,2-3H2,1H3;1H
• InChI key: OFXYKSLKNMTBHK-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Chlormethiazole serves as an anticonvulsant. It is useful in treating alcohol addiction and eclampsia. Chlormethiazole is also useful in treating convulsive status epilepticus. Long term administration of chlormethiazole leads to addiction to the drug.

GABA_A agonist; glycine receptor modulator.

Features and Benefits

This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H317,H318
• pcodes: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves