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Merck

B6295

Sigma-Aldrich

Benzalkonium chloride

BioXtra

Sinónimos:

Alkylbenzyldimethylammonium chloride, Alkyldimethylbenzylammonium chloride

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About This Item

Fórmula lineal:
C6H5CH2N(CH3)2RCl (R=C8H17 to C18H37)
Número de CAS:
Beilstein/REAXYS Number:
4062599
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25
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description

cationic

Quality Level

product line

BioXtra

assay

95.0-105.0% (calculated on dry substance)

form

(Solid or Semi-Solid or Viscous Liquid)

impurities

≤0.001% Phosphate
≤0.1% Insoluble matter
≤10% water

ign. residue

≤2%

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

[Cl-].CCCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1

InChI

1S/C19H34N.ClH/c1-4-5-6-7-8-9-10-14-17-20(2,3)18-19-15-12-11-13-16-19;/h11-13,15-16H,4-10,14,17-18H2,1-3H3;1H/q+1;/p-1

InChI key

TTZLKXKJIMOHHG-UHFFFAOYSA-M

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General description

Benzalkonium chloride is a cationic detergent that is a member of quaternary ammonium compounds (QACs). [1]

Application

Benzalkonium chloride has been used in a study to assess its action on epithelia conjunctival cells in vitro. [2] It has also been used in a study to investigate its effects on living rabbit cornea by in vivo Tandem scanning confocal microscopy. [3]

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Visite la Librería de documentos

Céline Portal et al.
PloS one, 12(3), e0174764-e0174764 (2017-03-30)
Modification of mucous cell density and gel-forming mucin production are established hallmarks of mucosal diseases. Our aim was to develop and validate a mouse model to study live goblet cell density in pathological situations and under pharmacological treatments. We created
H Ichijima et al.
Cornea, 11(3), 221-225 (1992-05-01)
The effects of benzalkonium chloride (BAK) on the living rabbit cornea were studied by in vivo Tandem scanning confocal microscopy (TSCM) and confirmed by conventional scanning electron microscopy (SEM). Two drops of saline or phosphate-buffered saline (PBS) containing BAK in
Dana Cervinkova et al.
Microbial drug resistance (Larchmont, N.Y.), 19(3), 160-167 (2012-12-22)
Conditions facilitating resistance to quaternary ammonium compounds (QACs) were investigated in Staphylococcus aureus SK982 exposed to benzalkonium chloride (BAC; a member of QACs) under various circumstances. S. aureus SK982 carrying the qacA gene encoding for resistance to QACs was grown
M De Saint Jean et al.
Investigative ophthalmology & visual science, 40(3), 619-630 (1999-03-06)
The aim of this study was to investigate the action of benzalkonium chloride (BAC), used as a preservative in most ophthalmic topical solutions, on epithelial conjunctival cells in vitro. A continuous human conjunctival cell line (Wong-Kilbourne derivative of Chang conjunctiva)
Eric G Romanowski et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 35(5), 311-314 (2019-04-11)
Purpose: Adenoviral conjunctivitis is the most common cause of conjunctivitis worldwide with no approved antiviral treatment. Benzalkonium chloride (BAK)

Questions

1–3 of 3 Questions  
  1. Benzalkonium chloride을 검색해봤을때 물에 잘 녹는다 나옵니다. 귀사에서 제공하는 SDS에는 물에 안녹는다나와있는데 확인된 정보가 맞을까요?

    1 answer
    1. Benzalkonium chloride is soluble in water. According to the Safety Data Sheet, moisture should be avoided with benzalkonium chloride as it can cause stability issues for the unused product.

      Helpful?

  2. What is the solubility?

    1 answer
    1. There are no specific solubility assays that are performed on this product. This is a very water-soluble compound.

      Helpful?

  3. Bjr, quelle est la durée possible d'utilisation d'un standard (cas du produit 12060, date de release 28/06/2023, lot BCCK4742) : +2 ans?, +3 ans..

    1 answer
    1. This product is not assigned an expiration date. It is assigned a recommended retest date of approximately 2 years after the quality release date. A recommended retest date is the time during which the product is expected to remain within established stability specifications, provided that it has been stored under defined conditions. After the Retest Date, product samples should be examined to ensure that the product is still in compliance with the established specifications.

      For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/quality-services.

      Helpful?

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