AV31926

Anti-RAX (AB2) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-RX, Anti-Retina and anterior neural fold homeobox
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: 37 kDa
• reactividad de especies: horse, mouse, human, guinea pig, bovine, rat
• concentración: 0.5 mg - 1 mg/mL
• técnicas: immunohistochemistry: suitable; western blot: suitable
• Nº de acceso NCBI: NP_038463
• Nº de acceso UniProt: Q9Y2V3
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... RAX(30062)

Descripción

Descripción general

Rabbit polyclonal anti-RAX (AB2) antibody reacts with bovine, canine, human, mouse, and rat retina and anterior neural fold homeobox factors.

Retina and anterior neural fold homeobox (RAX) is a paired-type homeobox gene expressed in the anterior neural fold and developing retina. RAX is involved in defining the eye field during early development wherein it participates in regulation of the proliferation and/or differentiation of retinal cells. Defects in RAX have been linked to the eye pathologies microphthalmia and anophthalmia.

Inmunógeno

Synthetic peptide directed towards the N terminal region of human RAX

Aplicación

Rabbit Anti-RAX (AB2) antibody can be used for western blot assays at a concentration of 0.5μg/ml.

Rabbit polyclonal anti-RAX (AB2) antibody is used to tag retina and anterior neural fold homeobox for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of retina and anterior neural fold homeobox in eye field/retinal development and eye pathologies such as microphthalmia and anophthalmia.

Acciones bioquímicas o fisiológicas

Retinal Homeobox Protein Rx (RAX) is a member of homeobox family of transcription factors. Mutations mouse and fish RAX lead to defects in retinal development and result in animal models of anophthalmia.

Secuencia

Synthetic peptide located within the following region: MHLPGCAPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKDDGILGT

Forma física

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable