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A6508

Sigma-Aldrich

L-Aspartic acid β-hydroxamate

>98%

Sinónimos:

AAH, HDX, LAH

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About This Item

Fórmula empírica (notación de Hill):
C4H8N2O4
Número de CAS:
1955-68-6
Peso molecular:
148.12
MDL number:
MFCD00050389
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24891095
NACRES:
NA.26

product name

L-Aspartic acid β-hydroxamate, serine racemase inhibitor

Quality Level

200

assay

>98%

form

powder

color

white to yellow

application(s)

detection

storage temp.

−20°C

SMILES string

N[C@@H](CC(=O)NO)C(O)=O

InChI

1S/C4H8N2O4/c5-2(4(8)9)1-3(7)6-10/h2,10H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key

ZBYVTTSIVDYQSO-REOHCLBHSA-N

Categorías relacionadas

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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M A Benhaim et al.
Science advances, 6(18), eaaz8822-eaaz8822 (2020-06-05)
The influenza virus hemagglutinin (HA) fusion protein has long been viewed as a "spring-loaded" fusion machine whereby activation at low pH initiates a rapid and irreversible cascade of conformational changes that drives the membrane fusion reaction. This mechanism has shaped
N Thomasset et al.
International journal of cancer, 49(3), 421-424 (1991-09-30)
D and L isomers of aspartic acid beta-hydroxamate (respectively DAH and LAH) were compared for their in vitro and in vivo activity against the murine leukemia L5178Y and their tolerance in vivo in DBA/2 mice. DAH and LAH displayed comparable
Yujiao Zhou et al.
Journal of immunology research, 2018, 9832467-9832467 (2018-08-18)
Dendritic cells (DCs) harboring tumor-associated antigen are supposed to be a potential immunotherapy for hepatocellular carcinoma (HCC). Aspartate-β-hydroxylase (AAH), an overexpressed tumor-associated cell surface protein, is considered as a promising biomarker and therapeutic target for HCC. In this study, we
Franck Danel et al.
Current drug discovery technologies, 8(1), 66-75 (2010-11-26)
Aminoacyl-tRNA synthetases (AARSs) are a structurally heterogeneous family of enzymes present in prokaryotes, archaea and eukaryotes. They catalyze the attachment of tRNA to its corresponding amino acid via an aminoacyl adenylate intermediate. Errors in protein synthesis will occur if an
Véronique Sauvé et al.
Nature structural & molecular biology, 25(7), 623-630 (2018-07-04)
Mutations in the ubiquitin ligase parkin are responsible for a familial form of Parkinson's disease. Parkin and the PINK1 kinase regulate a quality-control system for mitochondria. PINK1 phosphorylates ubiquitin on the outer membrane of damaged mitochondria, thus leading to recruitment
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