A3286

N-Acetil-D-glucosamina

BioReagent, suitable for cell culture

• Sinónimos: 2-Acetamido-2-desoxi-D-glucosa, D-GlcNAc
• Fórmula empírica (notación de Hill): C₈H₁₅NO₆
• Número de CAS: 7512-17-6
• Peso molecular: 221.21
• Beilstein/REAXYS Number: 1727589
• EC Number: 231-368-2
• MDL number: MFCD00061615
• UNSPSC Code: 12352201
• PubChem Substance ID: 24890757
• NACRES: NA.75

Propiedades

• product line: BioReagent
• assay: ≥95% (HPLC)
• form: powder
• technique(s): cell culture | mammalian: suitable
• mp: 211 °C (dec.) (lit.)
• storage temp.: −20°C
• SMILES string: CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
• InChI: 1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1
• InChI key: OVRNDRQMDRJTHS-RTRLPJTCSA-N

Descripción

General description

N-Acetylglucosamine (GlcNAc), a derivative of glucose is a monosaccharide. It is a white powder and is mildly sweet. It melts at 221°C. GlcNAc is 25% soluble in water. It is present in bromelain, ricin agglutinin and abrus agglutinin, in plants. In humans, it is present in tissue plasminogen activator, growth factors and hormones.

Application

N-Acetyl-D-glucosamine addition has been used:

• as a substrate to develop dot-blots
• as a substrate to reveal alkaline phosphatase in the immunohistochemical analysis
• to detect specific immune complexes in western blot analysis

Biochem/physiol Actions

N-Acetylglucosamine (GlcNAc) oligomer may have the ability to initiate factors for canine polymorphonuclear cells (PMN) in vivo. It possesses wound healing and chemotactic activity. GlcNAc and its derivatives are usually employed in preparing dietary supplements and also used in therapeutic development.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)