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48770

Sigma-Aldrich

Gentian violet

for microscopy (Bact., Hist.)

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About This Item

Beilstein/REAXYS Number:
8464808
MDL number:
MFCD00011750
UNSPSC Code:
12171500
PubChem Substance ID:
57651162
NACRES:
NA.47

grade

for microscopy (Bact., Hist.)

form

powder

density

1.19 g/cm3 at 20 °C

εmax

≥1300 at 580-595 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Cl-].CN(C)c1ccc(cc1)\C(c2ccc(cc2)N(C)C)=C3/C=C\C(C=C3)=[N+](/C)C

InChI

1S/C25H30N3.ClH/c1-26(2)22-13-7-19(8-14-22)25(20-9-15-23(16-10-20)27(3)4)21-11-17-24(18-12-21)28(5)6;/h7-18H,1-6H3;1H/q+1;/p-1

Inchi Key

ZXJXZNDDNMQXFV-UHFFFAOYSA-M

Categorías relacionadas

General description

mixture of crystal violet [C.I.No. 42555] and methyl violet [C.I.No. 42535]

Other Notes

Dye employed for preparing Gram stain

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Dam. 1 - Muta. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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P. Bock, ed.
Romeis Mikroskopische Technik null
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Journal of medicinal chemistry, 49(11), 3215-3224 (2006-05-26)
Three series of benzimidazole N-oxide derivatives were developed and were examined for their activity against trypanosomatid parasites (Trypanosoma cruzi and Leishmania spp.). 2H-benzimidazole 1,3-dioxides displayed remarkable in vitro activities against both parasites, with derivatives 28, 29, and 32 being the
Eufrânio N da Silva et al.
European journal of medicinal chemistry, 43(8), 1774-1780 (2007-11-30)
[1,2,3]-Triazole derivatives of nor-beta-lapachone were synthesized and assayed against the infective bloodstream trypomastigote form of Trypanosoma cruzi, the etiological agent of Chagas disease. All the derivatives were more active than the original quinones, with IC(50)/1 day values in the range
Jean Jerley Nogueira Silva et al.
Journal of medicinal chemistry, 51(14), 4104-4114 (2008-06-24)
The ruthenium complex, trans-[Ru(Bz)(NH 3) 4SO 2](CF 3SO 3) 2 1, Bz = benznidazole ( N-benzyl-2-(2-nitro-1 H-imidazol-1-yl)acetamide), is more hydrosoluble and more active (IC 50try/1 h = 79 +/- 3 microM) than free benznidazole 2 (IC 50try/1 h > 1
Marion Vanneste et al.
Scientific reports, 9(1), 1200-1200 (2019-02-06)
Epithelial-to-mesenchymal transition (EMT) is implicated in cancer metastasis and drug resistance. Specifically targeting cancer cells in an EMT-like state may have therapeutic value. In this study, we developed a cell imaging-based high-content screening protocol to identify EMT-selective cytotoxic compounds. Among
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