06863

Glycoursodeoxycholic acid

≥96.0% (TLC)

• Sinónimos: N-(3α,7β-Dihydroxy-5β-cholan-24-oyl)glycine, N-[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine, GUDCA, Glycylursodeoxycholic acid, Ursodeoxycholylglycine
• Fórmula empírica (notación de Hill): C₂₆H₄₃NO₅
• Número de CAS: 64480-66-6
• Peso molecular: 449.62
• MDL number: MFCD00137427
• UNSPSC Code: 12161900
• PubChem Substance ID: 329748294
• NACRES: NA.25

Propiedades

• biological source: synthetic
• Quality Level: 100
• assay: ≥96.0% (TLC)
• form: powder
• functional group: carboxylic acid
• SMILES string: [H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(NCC(O)=O)=O; [H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(NCC(O)=O)=O
• InChI: 1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21+,24+,25+,26-/m1/s1
• InChI key: GHCZAUBVMUEKKP-XROMFQGDSA-N

Descripción

Application

• Glycoursodeoxycholic Acid Alleviates Arterial Thrombosis via Suppressing Diacylglycerol Kinases Activity in Platelet.: Highlights the therapeutic potential of Glycoursodeoxycholic acid in alleviating arterial thrombosis by inhibiting diacylglycerol kinase activity in platelets (Yang et al., 2024).

Biochem/physiol Actions

Secondary bile acid derived from acyl glycine. Glycoursodeoxycholic Acid (GUDCA) is reported to have cytoprotective and anti-inflammatory effects.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable