PHR2533

Nicotine Related Compound C

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: (−)-Cotinine, (S)-1-Methyl-5-(3-pyridyl)-2-pyrrolidinone, S(−)-1-Methyl-5-(3-pyridyl)-2-pyrrolidone
• Fórmula empírica (notación de Hill): C₁₀H₁₂N₂O
• Número de CAS: 486-56-6
• Peso molecular: 176.22
• Beilstein/REAXYS Number: 83099
• MDL number: MFCD00077696
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to USP 1463348
• API family: nicotine
• form: solid
• packaging: pkg of 50 mg
• bp: 250 °C/150 mmHg (lit.)
• mp: 40-42 °C (lit.)
• application(s): pharmaceutical
• storage temp.: 2-8°C
• SMILES string: CN1[C@@H](CCC1=O)c2cccnc2
• InChI: 1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1
• InChI key: UIKROCXWUNQSPJ-VIFPVBQESA-N

Descripción

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Major metabolite of nicotine in humans.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC5258 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: 230.0 °F - closed cup
• flash_point_c: 110 °C - closed cup