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Merck

PHR1518

Supelco

Polydimethylsiloxane

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Dimethylpolysiloxane, Polydimethylsiloxane

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About This Item

Número de CAS:
Número MDL:
Código UNSPSC:
41116107
NACRES:
NA.24
En este momento no podemos mostrarle ni los precios ni la disponibilidad

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

Agency

traceable to Ph. Eur. S0600000
traceable to USP 1546300

familia API

polydimethylsiloxane

CofA

current certificate can be downloaded

envase

pkg of 1 g

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-30°C

cadena SMILES

[Si](=O)(C)C

InChI

1S/C2H6OSi/c1-4(2)3/h1-2H3

Clave InChI

SEUDSDUUJXTXSV-UHFFFAOYSA-N

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Descripción general

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Poly(dimethylsiloxane) [PDMS] is a polymer. It is a stable silicone rubber. It has been used as ion selective membrane for ion-sensitive field-effect transistors, as spring material in accelerometers, elastomer on a tactile sensor and as flexible encapsulation material in decouple sensors.[1]

Aplicación

Clear, colorless fluid polymer useful as a stationary phase in gas chromatography and as an anti-foaming agent.
It was used in a study performed to understand its molecular weight and molecular weight distribution by off-line coupling of GPC with MALDI mass spectrometer.[2]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAB7823 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Producto relacionado

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

609.8 °F - closed cup

Punto de inflamabilidad (°C)

321 °C - closed cup


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Certificados de análisis (COA)

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Robust and biodegradable elastomers based on corn starch and polydimethylsiloxane (PDMS).
Ceseracciu L
ACS Applied Materials & Interfaces, 7(6), 3742-3753 (2015)
Molecular weight distribution of poly (dimethylsiloxane) by combining matrix-assisted laser desorption/ionization time-of-flight mass spectrometry with gel-permeation chromatography fractionation.
Montaudo, Giorgio, et al.
Rapid Communications in Mass Spectrometry, 9.12, 1158-1163 (1995)

Questions

1–4 of 4 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. What is the concentration (ppm) of this product?

    1 answer
    1. This is a neat viscous liquid that is 99.98% pure. It is not a solution which would have a concentration value.

      Helpful?

  4. What is the MW of this? I need a 10K homopolymer Also what is it soluble in?

    1 answer
    1. Unfortunately, the molecular weight is not determined for this product. Solubility testing is not performed, however, this compound is reportedly soluble in non-polar solvents such as Chloroform, Toluene, and Diethyl Ether.

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