PHR1204

Benzophenone

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: Diphenyl ketone, Diphenylmethanone, NSC 8077
• Fórmula lineal: (C₆H₅)₂CO
• Número de CAS: 119-61-9
• Peso molecular: 182.22
• Beilstein: 1238185
• Número CE: 204-337-6
• Número MDL: MFCD00003076
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329823211
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to Ph. Eur. Y0000647
• presión de vapor: 1 mmHg ( 108 °C)
• familia API: benzophenone
• CofA: current certificate can be downloaded
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• bp: 305 °C (lit.)
• mp: 47-51 °C (lit.)
• aplicaciones: cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care; pharmaceutical (small molecule)
• Formato: neat
• temp. de almacenamiento: 2-30°C
• cadena SMILES: O=C(C1=CC=CC=C1)C2=CC=CC=C2
• InChI: 1S/C13H10O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H
• Clave InChI: RWCCWEUUXYIKHB-UHFFFAOYSA-N

Descripción

Descripción general

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Benzophenone is widely used in the manufacture of cosmetics and pharmaceuticals for its UV rays absorbing and fragrance retention abilities. Due to its ability to absorb ultraviolet radiations harmful in the form of UVA (320-400 nm) and UVB (290-320 nm), it is effective against skin disorders and skin cancer. It is used in the synthesis of antihistamines, hypnotics, and insecticides and is present as a potential impurity in diphenhydramine hydrochloride, phenytoin bulk powder, and phenytoin dosage forms.[1][2]

Aplicación

Benzophenone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic,[1][3] spectrophotometric[1][2] and polarographic[4] techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAC3932 in the slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H350,H373,H412
• Consejos de prudencia: P202 - P260 - P273 - P280 - P308 + P313 - P405
• Clasificaciones de peligro: Aquatic Chronic 3 - Carc. 1B - STOT RE 2 Oral
• Órganos de actuación: Liver,Kidney
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 280.4 °F - closed cup
• Punto de inflamabilidad (°C): 138 °C - closed cup