PHR1076

Metoprolol Tartrate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: Lopressor
• Fórmula lineal: (C₁₅H₂₅NO₃)₂ · C₄H₆O₆
• Número de CAS: 56392-17-7
• Peso molecular: 684.81
• EC Number: 260-148-9
• MDL number: MFCD00056257
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823099
• NACRES: NA.24

Propiedades

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to BP 540; traceable to Ph. Eur. M1830000; traceable to USP 1441301
• API family: metoprolol
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2
• InChI: 1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1
• InChI key: YGULWPYYGQCFMP-CEAXSRTFSA-N
• Gene Information: human ... ADRB1(153)

Descripción

General description

Metoprolol Tartrate is a β-blocking drug, showing antihypertensive and anti-ischemic effects. It is widely used in the treatment of hypertension and helps in controlling ventricular response in patients with atrial fibrillation.

Application

Metoprolol Tartrate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using densitometric technique and spectrophotometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA6905 in the slot below. This is an example certificate only and may not be the lot that you receive.

Información de seguridad

• pictograms: GHS08,GHS09
• signalword: Warning
• hcodes: H361d,H411
• pcodes: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Hazard Classifications: Aquatic Chronic 2 - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable