N4876

Ninhydrin

suitable for amino acid detection

• Sinónimos: 1,2,3-Indantrione monohydrate, 2,2-Dihydroxy-1,3-indanedione, Trioxohydrindene monohydrate
• Fórmula empírica (notación de Hill): C₉H₆O₄
• Número de CAS: 485-47-2
• Peso molecular: 178.14
• Beilstein/REAXYS Number: 1910963
• EC Number: 207-618-1
• MDL number: MFCD00003791
• UNSPSC Code: 12352100
• PubChem Substance ID: 24897715
• NACRES: NA.21

Propiedades

• form: powder
• Quality Level: 200
• mp: 250 °C (dec.) (lit.)
• solubility: ethanol: 100 mg/mL; H₂O: 50 mg/mL (with sonication)
• suitability: suitable for amino acid detection
• SMILES string: OC1(O)C(=O)c2ccccc2C1=O
• InChI: 1S/C9H6O4/c10-7-5-3-1-2-4-6(5)8(11)9(7,12)13/h1-4,12-13H
• InChI key: FEMOMIGRRWSMCU-UHFFFAOYSA-N

Descripción

General description

Ninhydrin is an important building block in organic synthesis and has been employed to prepare a variety of chemicals for complexing and/or sensing metal ions. It is an amino acid-sensitive reagent used for the preparation of Ruhemann′s purple.

Application

Ninhydrin can be used:

• For the detection of free amino groups in amino acids, peptides, and proteins.
• As a ligand for the Cu-catalyzed N-arylation of nitrogen-containing heterocycles with aryl and heteroaryl halides to synthesize N-arylheterocycles.
• As a reactant to synthesize aldols by reacting with active methylene compounds.

Used for the detection of free amino groups in amino acids, peptides and proteins.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319
• pcodes: P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves