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Merck

M1300000

Methylatropine bromide

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Atropine methyl bromide

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About This Item

Fórmula empírica (notación de Hill):
C18H26NO3 · Br
Número de CAS:
Peso molecular:
384.31
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

atropine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Br.C[N]1(C)[C@@H]2CC[C@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3

InChI

1S/C18H26NO3.BrH/c1-19(2)14-8-9-15(19)11-16(10-14)22-18(21)17(12-20)13-6-4-3-5-7-13;/h3-7,14-17,20H,8-12H2,1-2H3;1H/t14-,15+,16?,17?;

InChI key

YBFLMRSYEWDJEJ-ZNHDNBJUSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Methylatropine bromide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Hippocampus, 22(4), 914-925 (2011-05-05)
The vestibular system has been suggested to participate in spatial navigation, a function ascribed to the hippocampus. Vestibular stimulation during spatial navigation activates a hippocampal theta rhythm (4-10 Hz), which may enhance spatial processing and motor response. We hypothesize that
Carlito D D Martins et al.
Clinical and experimental pharmacology & physiology, 38(2), 89-93 (2010-12-15)
1. In the present study, we evaluated the autonomic balance of the heart in protein/energy-undernourished rats. 2. Rats were divided into two groups according to the diet they received after weaning: (i) the control group (n=16), given a 15% protein
Larissa C R Silveira et al.
Autonomic neuroscience : basic & clinical, 162(1-2), 35-41 (2011-03-25)
We have compared the effects of two types of physical training on the cardiac autonomic control in ovariectomized and sham-operated rats according to different approaches: double autonomic blockade (DAB) with methylatropine and propranolol; baroreflex sensibility (BRS) and spectral analysis of
Marina de Toledo Durand et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 300(2), R418-R427 (2010-11-26)
The present study investigated whether baroreflex control of autonomic function is impaired when there is a deficiency in NO production and the role of adrenergic and cholinergic mechanisms in mediating reflex responses. Electrical stimulation of the aortic depressor nerve in
Takahiko Yoshimoto et al.
The journal of physiological sciences : JPS, 61(5), 373-383 (2011-06-30)
In this study, after confirming the suppression of autonomic nervous function by isoflurane anesthesia using autonomic antagonists, we pharmacologically investigated the involvement of vasomotor and cardiac sympathetic functions in systolic blood pressure variability (SBPV) frequency components in conscious rats at

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