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Merck
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Key Documents

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90594

Supelco

Bisdemethoxycurcumin

analytical standard

Sinónimos:

(E,E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione, Bisdesmethoxycurcumin, Curcumin III, Didemethoxycurcumin

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About This Item

Fórmula empírica (notación de Hill):
C19H16O4
Número de CAS:
33171-05-0
Peso molecular:
308.33
Beilstein/REAXYS Number:
3149384
MDL number:
MFCD03419284
UNSPSC Code:
85151701
PubChem Substance ID:
329769933
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

Oc1ccc(cc1)\C=C\C(=O)CC(=O)\C=C\c2ccc(O)cc2

InChI

1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2/b11-5+,12-6+

InChI key

PREBVFJICNPEKM-YDWXAUTNSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number
BCCL6329
BCCH5959
BCCG7456
BCCF8041
BCCC8680

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Curcumin United States Pharmacopeia (USP) Reference Standard

USP

1151855

Curcumin

Curcumin primary reference standard

00280590

Curcumin

Hexahydrocurcumin analytical standard

Supelco

69727

Hexahydrocurcumin

Curcumin ≥94% (curcuminoid content), ≥80% (Curcumin)

Sigma-Aldrich

C7727

Curcumin

Curcumin from Curcuma longa (Turmeric), powder

Sigma-Aldrich

C1386

Curcumin

Tetrahydrocurcumin analytical standard

Supelco

50202

Tetrahydrocurcumin

Curcumin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2209

Curcumin

Tetrahydrocurcumin ≥96% (HPLC)

Sigma-Aldrich

SMB00370

Tetrahydrocurcumin

Jung Eun Kim et al.
Phytotherapy research : PTR, 17(5), 481-484 (2003-05-16)
Peroxynitrite is a cytotoxic intermediate produced by the reaction between the superoxide anion (O(2)) and nitric oxide (NO). The aim of this study was to investigate the scavenging effects of Curcuma longa L. on authentic peroxynitrite, and further studies are
James R Fuchs et al.
Bioorganic & medicinal chemistry letters, 19(7), 2065-2069 (2009-03-03)
Two series of curcumin analogues, a total of twenty-four compounds, were synthesized and evaluated. The most potent compound, compound 23, showed potent growth inhibitory activities on both prostate and breast cancer lines with IC(50) values in sub-micromolar range, fifty times
Xu Qiu et al.
Bioorganic & medicinal chemistry, 16(17), 8035-8041 (2008-08-06)
Series of curcumin derivatives were synthesized; the inhibitory activities on thioredoxin reductase (TrxR) of all analogues were evaluated by DTNB assay in vitro. It is found that most of the analogues can inhibit TrxR in the low micromolar range; Structure-activity
Zhongfa Liu et al.
Bioorganic & medicinal chemistry letters, 19(3), 706-709 (2008-12-30)
Molecular docking of the interaction of curcumin and DNMT1 suggested that curcumin covalently blocks the catalytic thiolate of C1226 of DNMT1 to exert its inhibitory effect. This was validated by showing that curcumin inhibits the activity of M. SssI with
W Chearwae et al.
Biochemical pharmacology, 68(10), 2043-2052 (2004-10-13)
P-glycoprotein (Pgp, ABCB1) is an ATP-dependent drug efflux pump linked to development of multidrug resistance (MDR) in cancer cells. Previously [Biochem Pharmacol 2002;64:573-82], we reported that a curcumin mixture could modulate both function and expression of Pgp. This study focuses
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