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Merck

51825

Supelco

Bemotrizinol

analytical standard

Sinónimos:

2,4-Bis[4-(2-ethylhexyloxy)-2-hydroxyphenyl]-6-(4-methoxyphenyl)-1,3,5-triazine

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About This Item

Fórmula empírica (notación de Hill):
C38H49N3O5
Número de CAS:
Peso molecular:
627.81
Beilstein/REAXYS Number:
11322254
MDL number:
UNSPSC Code:
77101502
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

composition

carbon content, 72.70% (theory)
hydrogen content, 7.87% (theory)
nitrogen content, 6.69% (theory)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

77-85 °C

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

CCCCC(CC)COc1ccc(c(O)c1)-c2nc(nc(n2)-c3ccc(OCC(CC)CCCC)cc3O)-c4ccc(OC)cc4

InChI

1S/C38H49N3O5/c1-6-10-12-26(8-3)24-45-30-18-20-32(34(42)22-30)37-39-36(28-14-16-29(44-5)17-15-28)40-38(41-37)33-21-19-31(23-35(33)43)46-25-27(9-4)13-11-7-2/h14-23,26-27,42-43H,6-13,24-25H2,1-5H3

InChI key

XVAMCHGMPYWHNL-UHFFFAOYSA-N

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General description

Bemotrizinol is a fat-soluble organic UV filter that belongs to the family of methoxybenzenes. It is commonly used as a constituent of sunscreen products due to its ability to absorb UV-A radiations. It is commonly sold as Tinosorb S and Escalol S.

Application

The analytical standard can also be used as follows:
  • Multi-residue analysis of five UV filters in sunscreen lotion and human outermost skin samples by ultrasound-vortex-assisted DLLME (US-VA-DLLME) and high-performance liquid chromatography-diode array detection (HPLC-DAD)
  • Quantification of nine organic UV filters in coastal sand samples using an optimized high-performance liquid chromatography (HPLC) method based on a biphenyl core-shell column, in combination with UV and fluorescence detection
  • Determination of the analyte in topical pharmaceutical formulations by reversed-phase high-performance liquid chromatography method (RP-HPLC).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

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Visite la Librería de documentos

Development and validation of a stability indicating RP-HPLC method for the determination of two sun protection factors (Koptrizon and Tinosorb S) in topical pharmaceutical formulations using experimental designs
Roy C and Chakrabarty J
ISRN Chromatography, 2013 (2013)
Diogo Noin de Oliveira et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 988, 13-19 (2015-03-07)
Sunlight exposure causes several types of injury to humans, especially on the skin; among the most common harmful effects due to ultraviolet (UV) exposure are erythema, pigmentation and lesions in DNA, which may lead to cancer. These long-term effects are

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