37022

(−)-Scopolamine hydrochloride

analytical standard

• Sinónimos: Hyoscine hydrochloride, Scopine tropate
• Fórmula empírica (notación de Hill): C₁₇H₂₁NO₄ · HCl
• Número de CAS: 55-16-3
• Peso molecular: 339.81
• Beilstein/REAXYS Number: 4168778
• EC Number: 200-225-6
• MDL number: MFCD00058096
• UNSPSC Code: 85151701
• PubChem Substance ID: 329755587
• NACRES: NA.24

Propiedades

• grade: analytical standard
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: neat
• storage temp.: −20°C
• SMILES string: Cl.[H][C@]12C[C@H](C[C@]([H])(N1C)[C@]3([H])O[C@]23[H])OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.ClH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1
• InChI key: KXPXJGYSEPEXMF-MOUKNHLCSA-N
• Gene Information: human ... CHRM1(1128)

Descripción

General description

(−)-Scopolamine hydrochloride belongs to the class of naturally occurring tropane alkaloids of medicinal interest, found in several members of the Solanaceae family, commonly Atropa belladonna and representatives of the genera Datura and Duboisia.

For the analysis of the phytotoxins.

Application

(−)-Scopolamine hydrochloride may be used as a precursor for the preparation of scopolamine, employed as an analytical standard for the quantification of the scopolamine in the floral nectar and plant organs of Datura species using various chromatographic techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

Reconstitution

Dried down, concentration of (S)-(-)-Scopolamine (free base) after reconstitution ~100μg/mL

Analysis Note

purity : ≥96.0% (HPLC)

Información de seguridad

• Pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H300 + H310 + H330,H317,H318
• pcodes: P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Sens. 1
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable