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Key Documents

MAB3321

Sigma-Aldrich

Anti-MMP-13 Antibody, clone 181-15A12

clone 181-15A12, Chemicon®, from mouse

Sinónimos:

Collagenase-3

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

181-15A12, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... MMP13(4322)

Specificity

Reacts with precursor and active forms of human MMP-13 and does not cross-react with human MMP-1, 2, 3, 7, 8, 9. This is a purified mouse moncolonal antibody to recombinant human matrix metalloproteinase 13 (human MMP-13, procollagenase-3).

Application

Anti-MMP-13 Antibody, clone 181-15A12 detects level of MMP-13 & has been published & validated for use in ELISA, WB, IH(P).
Immunoblotting

Immunohistochemistry on paraffin-embedded tissue sections.
Research Category
Cell Structure
Research Sub Category
MMPs & TIMPs

Physical form

Format: Purified
Purified immunoglobulin to recombinant human matrix metalloproteinase 13 (human MMP-13, procollagenase-3). Liquid in 0.1 M PBS, pH 7.0 containing 4% protease free bovine serum albumin.

Storage and Stability

Maintain at -20°C for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Manufactured by Daiichi Fine Chemical Co., Ltd

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Development of a solid-phase assay for analysis of matrix metalloproteinase activity.
Lauer-Fields, JL; Nagase, H; Fields, GB
Journal of biomolecular techniques : JBT null
M R Junttila et al.
Oncogene, 26(36), 5267-5279 (2007-03-06)
Recent studies indicate that the specificity of p38 mitogen-activated protein kinase (MAPK)-mediated cellular stress responses is determined by the expression pattern of the distinct p38 isoforms. Here, we have analysed the function of distinct p38 isoforms in the growth and
Jorge González-Zamora et al.
Antioxidants (Basel, Switzerland), 12(4) (2023-04-28)
Age-related macular degeneration (AMD) is a leading cause of severe vision loss in older individuals in developed countries. Despite advances in our understanding of AMD, its pathophysiology remains poorly understood. Matrix metalloproteinases (MMPs) have been proposed to play a role
J M Del Casar et al.
Breast cancer research and treatment, 116(1), 39-52 (2009-02-26)
An immunohistochemical study was performed using tissue arrays and specific antibodies against MMPs -1, -2, -7, -9, -11, -13, -14, and TIMPs -1, -2 and -3. More than 5,000 determinations on cancer specimens from 124 patients with invasive breast cancer
Elizabeth H Stephens et al.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 13(6), 447-458 (2010-06-12)
At birth, the mechanical environment of valves changes radically as fetal shunts close and pulmonary and systemic vascular resistances change. Given that valves are reported to be mechanosensitive, we investigated remodeling induced by perinatal changes by examining compositional and structural

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