609312

Thyroglobulin, Human Thyroid

• Sinónimos: Thyroglobulin, Human Thyroid
• Número de CAS: 9010-34-8
• Número MDL: MFCD00077045
• Código UNSPSC: 12352202
• NACRES: NA.25

Propiedades

• origen biológico: human thyroid
• Nivel de calidad: 100
• Ensayo: ≥95% (PAGE)
• Formulario: lyophilized
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C

Descripción

Descripción general

Native thyroglobulin, consisting of two polypeptide monomers of 330 kDa each, purified from human thyroid. This protein is an excellent source of N-linked glycans of various structures, including sialylated core fucose and oligomannose oligosaccharides. Also, Gal-3-SO₄ and GalNAc-6-SO₄ residues located in a single multi-branched complex type glycan have been reported in calf thymus and human proteins. When subjected to native PAGE this protein shows a band at

~660 kDa, representing the dimeric form, and another band at ~330 kDa, representing the monomeric form.

Advertencia

Toxicity: Standard Handling (A)

Forma física

Lyophilized from 20 mM NH₄HCO₃.

Nota de preparación

Prepared from tissues of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitución

Reconstitute in phosphate buffer, containing 150 mM NaCl, pH >7.0.

Otras notas

Rawitch, A.B., et al. 1993. Arch. Biochem. Biophys. 300, 271.
Black, E.G., and Sheppard, M.C. 1991. Clin. Endocrinol. 35, 519.
Spiro, R.G., and Bhoyroo, V.D. 1988. J. Biol. Chem. 263, 14351.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3