219008

Catalase, Human Erythrocytes

Catalase from human erythrocytes, CAS 9001-05-2. Composed of four identical subunits of ~60 kDa each.

• Sinónimos: Catalase, Human Erythrocytes
• Número de CAS: 9001-05-2
• Comisión internacional de enzimas: 1.11.1.6 (BRENDA, IUBMB)
• MDL number: MFCD00081483
• UNSPSC Code: 12352202
• NACRES: NA.25

Propiedades

• Quality Level: 100
• assay: ≥95% (SDS-PAGE)
• form: liquid
• specific activity: ≥50,000 units/mg protein
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −20°C
• InChI: 1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3
• InChI key: NUVBSKCKDOMJSU-UHFFFAOYSA-N

Descripción

General description

Catalase, along with superoxide dismutase and glutathione peroxidase, controls the levels of oxygen-derived free radicals in mammalian cells. Together these molecules may function as a somatic oxidant defense. Prevents apoptosis in cultured rat ovarian follicles.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of enzyme that will decompose 1.0 µmol H₂O₂ per min at 25°C, pH 7.0.

Physical form

In 50 mM Tris, pH 8.0.

Preparation Note

Prepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Tilly, J.L., and Tilly, K.I. 1995. Endocrinology136, 242.
Bonaventura, J., et al. 1972. Arch. Biochem. Biophys.150, 606.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: nwg