07-843

Anti-phospho-IRS1 (Ser616) Antibody

Upstate^®, from rabbit

• Sinónimos: IRS-1, Insulin Receptor Substrate 1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• manufacturer/tradename: Upstate^®
• technique(s): immunocytochemistry: suitable; western blot: suitable
• isotype: IgG
• NCBI accession no.: NM_000208.2; NM_001079817.1
• UniProt accession no.: P06213
• shipped in: dry ice
• target post-translational modification: phosphorylation (pSer616)
• Gene Information: human ... INSR(3643)

Descripción

Specificity

Human IRS1 (Insulin Receptor Substrate 1) phosphorylated on Serine residue 616. Sequence 100% homologous with mouse, rat, and pig.

Predicted to cross-react with mouse and rat based on 100% sequence homology, but have not been tested.

Immunogen

Peptide corresponding to amino acid region encompassing the human, mouse, and rat phospho-IRS-1 (Ser616)

Application

Immunoblot Analysis: 0.5 μg/mL dilutions of this antibody detected phospho-IRS1 (Ser616) in RIPA lysates from TPA treated CHO cells transfected with human IRS1.

Research Category
Signaling

Research Sub Category
Insulin/Energy Signaling

anti-phospho-IRS1 (Ser616) Antibody is an antibody against phospho-IRS1 (Ser616) for use in IC & WB.

Quality

Evaluated by immunoblot.

Target description

165 kDa

Physical form

100 μL of affinity purified rabbit polyclonal IgG in PBS (without Mg²⁺ and Ca²⁺), pH 7.3, containing 1.0 mg/mL BSA (IgG, protease free), 0.05% sodium azide and 50% glycerol.

Affinity purified

Storage and Stability

1 year at -20°C.
Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/ thaw cycles, which may damage IgG and affect product performance.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2