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Merck
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Key Documents

07-351

Sigma-Aldrich

Anti-NR3B Antibody

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

Specificity

NR3B

Immunogen

peptide corresponding to amino acids 916-930 (C-RRVRRAVVERERRVR) of mouse NR3B

Application

This Anti-NR3B Antibody is validated for use in WB for the detection of NR3B.

Quality

routinely evaluated by immunoblot on a rat brain microsomal protein preparation

Target description

98kDa

Physical form

Format: Purified

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


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Visite la Librería de documentos

M Nishi et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(23), RC185-RC185 (2001-11-22)
We have identified a novel glutamate receptor subunit on the human and mouse genome. Cloning of the mouse cDNA revealed a protein consisting of 1003 amino acids encoded by at least nine exons. This protein showed the highest similarity (51%)
Keiko Matsuda et al.
Brain research. Molecular brain research, 100(1-2), 43-52 (2002-05-15)
We report the cloning and characterization of a novel NMDA receptor subunit cDNA, which encodes a predicted polypeptide of 1003 amino acids. Phylogenic analysis indicates that this new subunit is most closely related to NR3A. Therefore, we term it NR3B.
Scott E Hemby et al.
Methods in molecular biology (Clifton, N.J.), 566, 69-83 (2010-01-09)
The ability to model aspects of human addictive behaviors in laboratory animals provides an important avenue for gaining insight into the biochemical alterations associated with drug intake and the identification of targets for medication development to treat addictive disorders. The
Jon E Chatterton et al.
Nature, 415(6873), 793-798 (2002-02-02)
The N-methyl-D-aspartate subtype of glutamate receptor (NMDAR) serves critical functions in physiological and pathological processes in the central nervous system, including neuronal development, plasticity and neurodegeneration. Conventional heteromeric NMDARs composed of NR1 and NR2A-D subunits require dual agonists, glutamate and
Region specific regulation of NR1 in rhesus monkeys following chronic antipsychotic drug administration.
O'Connor JA, Hasenkamp W, Horman BM, Muly EC, Hemby SE.
Biological Psychiatry null

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