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Merck
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Key Documents

07-344

Sigma-Aldrich

Anti-CPI-17 Antibody

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, pig, mouse, human, rabbit, bovine

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_033256

UniProt accession no.

Q96A00

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

bovine ... Ppp1R14A(615348)
human ... PPP1R14A(94274)
mouse ... Ppp1R14A(68458)
pig ... Ppp1R14A(397610)
rat ... Ppp1R14A(114004)

Specificity

CPI-17

Immunogen

Recombinant protein, full length pig CPI-17

Application

Anti-CPI-17 Antibody is an antibody against CPI-17 for use in WB.
NOT cross-reactive in yeast.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

Quality

routinely evaluated by immunoblot on RIPA lysates from mouse brain nuclear fraction and pig carotid artery tissue extract

Target description

22kDa

Physical form

Format: Purified
PBS, 0.02% sodium azide before the addition of glycerol to 10%
Protein A chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Cerebellar long-term synaptic depression requires PKC-mediated activation of CPI-17, a myosin/moesin phosphatase inhibitor
Eto, M., et al
Neuron, 36, 1145-1158 (2002)
Ayça Toprak Semiz et al.
Life sciences, 255, 117834-117834 (2020-05-27)
Hydrogen sulfide (H2S) is shown in ocular tissues and suggested to involve in the regulation of retinal circulation. However, the mechanism of H2S-induced relaxation on retinal artery is not clarified yet. Herein, we aimed to evaluate the role of several
Solution NMR structure of the myosin phosphatase inhibitor protein CPI-17 shows phosphorylation-induced conformational changes responsible for activation.
Ohki, S, et al.
Journal of Molecular Biology, 314, 839-849 (2001)
Sara R Turner et al.
Scientific reports, 9(1), 481-481 (2019-01-27)
The role of the smoothelin-like 1 (SMTNL1) protein in mediating vascular smooth muscle contractile responses to intraluminal pressure was examined in resistance vessels. Mesenteric arterioles from wild type (WT) and SMTNL1 global knock-out (KO) mice were examined with pressure myography.
Xiang-Dong Ren et al.
Journal of cell science, 117(Pt 16), 3511-3518 (2004-07-01)
Serum-soluble factors play a dominant role in the activation of the small GTPase RhoA. Cell adhesion also modulates RhoA activity but the effect is modest in the absence of serum. Here, we show that cell adhesion is required for serum-stimulated
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