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V-016

Supelco

Nicotinamide

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Sinónimos:

Nicotinamide, Vitamin B3, Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin PP

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About This Item

Fórmula empírica (notación de Hill):
C6H6N2O
Número de CAS:
98-92-0
Peso molecular:
122.12
Beilstein:
383619
Número CE:
200-659-6
Número MDL:
MFCD00006395
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329828959
NACRES:
NA.24

grado

certified reference material

Nivel de calidad

300

Formulario

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

concentración

1.0 mg/mL in methanol

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

128-131 °C (lit.)

aplicaciones

clinical testing
clinical testing

Formato

single component solution

temp. de almacenamiento

−20°C

cadena SMILES

NC(=O)c1cccnc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

Clave InChI

DFPAKSUCGFBDDF-UHFFFAOYSA-N

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Descripción general

Nicotinamide is also known as niacinamide or nicotinic acid amide. It is the water-soluble form of Vitamin B3 found in plant and animal foods and mostly used as a dietary supplement.

Aplicación

This certified solution standard is suitable for a variety of testing applications including quality control testing by HPLC for pharmaceutical preparations or dietary supplements.
Nicotinamide may be used as an analytical reference standard for the determination of the analyte in energy drinks by planar chromatography-multiple detection with confirmation by electrospray ionization mass spectrometry and in pharmaceutical formulations, by UV-visible spectrophotometry and multivariate analysis.

Acciones bioquímicas o fisiológicas

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

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Simultaneous determination of riboflavin, pyridoxine, nicotinamide, caffeine and taurine in energy drinks by planar chromatography-multiple detection with confirmation by electrospray ionization mass spectrometry
Aranda M and Morlock G
Journal of Chromatography A, 1131(1-2), 253-260 (2006)
Simultaneous determination and classification of riboflavin, thiamine, nicotinamide and pyridoxine in pharmaceutical formulations, by UV-visible spectrophotometry and multivariate analysis
Lopez-de-Alba LP, et al.
Journal of the Brazilian Chemical Society, 17(4), 715-722 (2006)
J Gore et al.
Journal of economic entomology, 106(3), 1430-1439 (2013-07-20)
Cotton aphid, Aphis gossypii Glover, has a history of developing resistance to novel insecticides. A program is needed to monitor cotton aphid susceptibility to new insecticides. Concentration-mortality bioassays were conducted from 2008 to 2011 to monitor the susceptibility of cotton
Robert J Motzer et al.
The Lancet. Oncology, 14(6), 552-562 (2013-04-20)
In a phase 3 trial comparing the efficacy and safety of axitinib versus sorafenib as second-line treatment for metastatic renal cell carcinoma, patients given axitinib had a longer progression-free survival (PFS). Here, we report overall survival and updated efficacy, quality
Takeshi Ueda et al.
Japanese journal of clinical oncology, 43(6), 616-628 (2013-05-01)
Axitinib is a potent and selective second-generation inhibitor of vascular endothelial growth factor receptors 1, 2 and 3. The efficacy and safety of axitinib in Japanese patients with metastatic renal cell carcinoma were evaluated. A subgroup analysis was conducted in
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