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T-030

Supelco

Trazodone hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C19H23Cl2N5O
Número de CAS:
25332-39-2
Peso molecular:
408.32
Número CE:
200-659-6
Código UNSPSC:
41116107
NACRES:
NA.24
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grado

certified reference material

Nivel de calidad

300

Formulario

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

concentración

1.0 mg/mL in methanol (as free base)

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicaciones

clinical testing

Formato

single component solution

temp. de almacenamiento

2-8°C

cadena SMILES

Cl.Clc1cccc(c1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2

InChI

1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H

Clave InChI

OHHDIOKRWWOXMT-UHFFFAOYSA-N

Información sobre el gen

human ... HTR2A(3356) , HTR2C(3358) , SLC6A4(6532)

Descripción general

Trazodone is a antidepressant drug sold under trade names such as Desyrel® and Oleptro® for treatment of anxiety disorder, depression, and insomnia. Trazadone, a serotonin antagonist and reuptake inhibitor (SARI), also has anti-anxiety and hypnotic effects. This certified Snap-N-Spike® solution is suitable for use in clinical toxicology, forensic analysis, or urine drug testing methods by LC-MS/MS or GC/MS.

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Desyrel is a registered trademark of Aziende Chimiche Riunite Angelini Francesco (A.C.R.A.F.) S.p.A.
Oleptro is a registered trademark of Angelini Pharma Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

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Ramez Ghanbari et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 22(7), 518-526 (2011-12-14)
Previous study has documented the long-term effects of the antidepressant trazodone on the serotonin (5-HT) system. The present work examined the impact of sustained trazodone on ventral tegmental area (VTA) dopamine (DA) and locus ceruleus (LC) norepinephrine (NE) neurons firing
A Georgotas et al.
Pharmacotherapy, 2(5), 255-265 (1982-09-01)
Trazodone is a new antidepressant agent that was recently introduced in the United States. It has a unique pharmacological profile that is not typical of either tricyclic or monoamine oxidase inhibitor antidepressants. As such it represents a new class of
Andrea Fagiolini et al.
CNS drugs, 26(12), 1033-1049 (2012-11-30)
Trazodone is a triazolopyridine derivative that belongs to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs). The drug is approved and marketed in several countries worldwide for the treatment of major depressive disorder (MDD) in adult patients. In
Marek Jarema et al.
Psychiatria polska, 45(4), 611-625 (2012-01-12)
The pharmacological properties and possible clinical use of trazodon in the treatment of depression are presented. Trazodon is the only antidepressant from the SARI (Serotonin Antagonists and Reuptake Inhibitors) group available in Poland. It has a wide pharmacodynamic profile (being
Arnaud Devresse et al.
Acta gastro-enterologica Belgica, 75(2), 263-265 (2012-08-09)
We present the case of a 26-year-old man with schizoid personality disorder who suffered from a very focal and transparietal necrosis of the sigmoid after an overdose of atypical neuroleptics. This is a singular, rather unknown and potentially lethal side
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