860512P

C12 Ceramide (d18:1/12:0)

Avanti Research^™ - A Croda Brand

• Sinónimos: N-lauroyl-D-erythro-sphingosine
• Fórmula empírica (notación de Hill): C₃₀H₅₉NO₃
• Número de CAS: 74713-60-3
• Peso molecular: 481.79
• MDL number: MFCD02259133
• UNSPSC Code: 12352211
• NACRES: NA.25

Propiedades

• form: powder
• packaging: pkg of 1 × 10 mg (860512P-10mg); pkg of 1 × 25 mg (860512P-25mg); pkg of 1 × 5 mg (860512P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C30H59NO3/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-29(33)28(27-32)31-30(34)26-24-22-20-17-12-10-8-6-4-2/h23,25,28-29,32-33H,3-22,24,26-27H2,1-2H3,(H,31,34)/b25-23+/t28-,29+/m0/s1
• InChI key: HXFPPRPLRSPNIB-VARSQMIESA-N

Descripción

General description

C12 Ceramide (d18:1/12:0) is a synthetic ceramide containing sphingosine with lauric acid.

Application

C12 Ceramide (d18:1/12:0) or N-lauroyl-D-erythro-sphingosine has been used:

• as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions[1]
• as an internal standard for lipid extraction in U87MG (human glioma cell line)[2]
• as an internal standard for the quantification of ceramide using liquid chromatography-mass spectrometry (LC-MS) in rat tissues[3]

Biochem/physiol Actions

Ceramides are signaling sphingolipids,[4] which are implicated in regulating stress responses and inflammation.[5] It also regulates cell growth arrest, differentiation and apoptosis.[4]

Packaging

5 mL Amber Glass Screw Cap Vial (860512P-10mg)

5 mL Amber Glass Screw Cap Vial (860512P-25mg)

5 mL Amber Glass Screw Cap Vial (860512P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3