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Merck

855775P

Avanti

18:0 Lyso PC

Avanti Research - A Croda Brand

Sinónimos:

1-octadecanoyl-sn-glycero-3-phosphocholine; PC(18:0/0:0)

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About This Item

Fórmula empírica (notación de Hill):
C26H54NO7P
Número de CAS:
Peso molecular:
523.68
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-stearoyl-2-hydroxy-sn-glycero-3-phosphocholine

assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

powder

packaging

pkg of 1 × 1 g (855775P-1g)
pkg of 1 × 200 mg (855775P-200mg)
pkg of 1 × 25 mg (855775P-25mg)
pkg of 1 × 500 mg (855775P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCCCCCC)=O

InChI

1S/C26H54NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(29)32-23-25(28)24-34-35(30,31)33-22-21-27(2,3)4/h25,28H,5-24H2,1-4H3

InChI key

IHNKQIMGVNPMTC-UHFFFAOYSA-N

Application

18:0 Lyso PC has been used:
  • to functionalize carbon nanotubes (CNTs) for the development of methods to attach DNA to CNTs
  • to increase the level of lysophosphatidic acid (LPA) in mouse
  • to induce TNF receptor associated factor 3 interacting protein 2 (TRAF3IP2) expression in endothelial cells (EC)

Packaging

20 mL Clear Glass Screw Cap Vial (855775P-1g)
20 mL Clear Glass Screw Cap Vial (855775P-500mg)
5 mL Amber Glass Screw Cap Vial (855775P-200mg)
5 mL Amber Glass Screw Cap Vial (855775P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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OxLDL induces endothelial dysfunction and death via TRAF3IP2: inhibition by HDL3 and AMPK activators
Valente AJ, et al.
Free radical biology & medicine, 70, 117-128 (2014)
Optimising DNA binding to carbon nanotubes by non-covalent methods
Vanesa Sanz
Carbon, 49(5), 1775-1781 (2011)
Dumindika A Siriwardane et al.
International journal of pharmaceutics, 578, 119077-119077 (2020-01-29)
Identification and quantification of excipient related degradation products in the liposomal formulation is important, as they may impact the safety and efficacy of the drug. Phospholipids are one of the major excipients in liposome drugs composing the lipid bilayer, and
Ieva Ailte et al.
Scientific reports, 6, 30336-30336 (2016-07-28)
Shiga toxin (Stx), an AB5 toxin, binds specifically to the neutral glycosphingolipid Gb3 at the cell surface before being transported into cells. We here demonstrate that addition of conical lysophospholipids (LPLs) with large head groups inhibit Stx binding to cells
Anthony J Valente et al.
Free radical biology & medicine, 70, 117-128 (2014-02-25)
Oxidized low-density lipoprotein (oxLDL) induces endothelial cell death through the activation of NF-κB and AP-1 pathways. TRAF3IP2 is a redox-sensitive cytoplasmic adapter protein and an upstream regulator of IKK/NF-κB and JNK/AP-1. Here we show that oxLDL-induced death in human primary

Artículos

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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