S5502
Succinic dihydrazide
96%
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About This Item
Fórmula lineal:
H2NNHCOCH2CH2CONHNH2
Número de CAS:
Peso molecular:
146.15
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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assay
96%
mp
170-171 °C (lit.)
SMILES string
NNC(=O)CCC(=O)NN
InChI
1S/C4H10N4O2/c5-7-3(9)1-2-4(10)8-6/h1-2,5-6H2,(H,7,9)(H,8,10)
InChI key
HCOMFAYPHBFMKU-UHFFFAOYSA-N
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Nucleosides, nucleotides & nucleic acids, 30(7-8), 577-584 (2011-09-06)
An efficient method for the synthesis of DNA or RNA oligonucleotide 2'-hydrazides is described. Fully deprotected oligonucleotides containing a hydrazide group at the 2'-position of a uridine residue were obtained by a novel two-step procedure: periodate cleavage of an oligonucleotide
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Analytical biochemistry, 277(1), 127-134 (1999-12-28)
We developed a convenient method for the synthesis of dextran-based multivalent probes containing N-linked oligosaccharides which is efficient even in a small scale. Oligosaccharides were derivatized with succinic dihydrazide and dimethylamine borane under a mild acidic condition. The derivatized oligosaccharides
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In amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD), cytoplasmic aggregates of hyperphosphorylated TDP-43 accumulate and colocalize with some stress granule components, but how pathological TDP-43 aggregation is nucleated remains unknown. In Drosophila, we establish that downregulation of tankyrase, a poly(ADP-ribose)
M F Turchinskiĭ et al.
Bioorganicheskaia khimiia, 15(10), 1341-1345 (1989-10-01)
A two-step chemical method of introduction of nonradioactive labels in DNA was proposed. At first step DNA is modified by succinic dihydrazide at pH 5.0 and 95 degrees C, or at pH 4.5 and 37 degrees C in presence of
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