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Key Documents

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F2003

Sigma-Aldrich

Flavone

≥99.0%

Sinónimos:

2-Phenyl-4H-1-benzopyran-4-one, 2-Phenylchromone

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About This Item

Fórmula empírica (notación de Hill):
C15H10O2
Número de CAS:
525-82-6
Peso molecular:
222.24
Beilstein/REAXYS Number:
157598
EC Number:
208-383-8
MDL number:
MFCD00006825
UNSPSC Code:
12352100
PubChem Substance ID:
57654180
NACRES:
NA.22

assay

≥99.0%

form

powder

mp

94-97 °C (lit.)

SMILES string

O=C1C=C(Oc2ccccc12)c3ccccc3

InChI

1S/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H

InChI key

VHBFFQKBGNRLFZ-UHFFFAOYSA-N

Gene Information

human ... ADORA3(140) , ANPEP(290) , CYP1A2(1544)
mouse ... Hexa(15211)
rat ... Adora1(29290) , Adora2a(25369) , Ar(24208) , Gabra2(29706)

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

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trans-Chalcone 97%

Sigma-Aldrich

136123

trans-Chalcone

Aaron Ciechanover et al.
Experimental & molecular medicine, 47, e147-e147 (2015-03-15)
Mammalian cells remove misfolded proteins using various proteolytic systems, including the ubiquitin (Ub)-proteasome system (UPS), chaperone mediated autophagy (CMA) and macroautophagy. The majority of misfolded proteins are degraded by the UPS, in which Ub-conjugated substrates are deubiquitinated, unfolded and cleaved
León Jesús German-Ponciano et al.
Neurochemistry international, 140, 104850-104850 (2020-09-23)
Chrysin (5,7-dihydroxyflavone), a nutraceutical flavonoid present in diverse plants, has a backbone structure shared with the flavone backbone, with additional hydroxyl groups that confers its antioxidant properties and effects at the GABAA receptor complex. However, whether these effects are due
Yaoyao Peng et al.
Antioxidants (Basel, Switzerland), 8(5) (2019-05-24)
Feijoa fruit is becoming increasingly popular, yet limited studies have focused on the antioxidant capacity and phenolic profiling of its extracts. In this research, optimization of phenolic extraction from feijoa flesh, peel, and whole fruit from four New Zealand grown
Xiaodan Zhao et al.
Water research, 119, 126-135 (2017-04-30)
The kinetics for the reactions of hypoiodous acid (HOI) with various phenols (phenol, 4-nitrophenol, 4-hydroxybenzoic acid), 3-oxopentanedioic acid (3-OPA) and flavone were investigated in the pH range of 6.0-11.0. The apparent second order rate constants for the reactions of HOI
Tanya Welgemoed et al.
Frontiers in plant science, 11, 191-191 (2020-04-02)
Gray leaf spot (GLS) disease in maize, caused by the fungus Cercospora zeina, is a threat to maize production globally. Understanding the molecular basis for quantitative resistance to GLS is therefore important for food security. We developed a de novo
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