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CDS020796
Glycyrrhizin
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About This Item
Fórmula empírica (notación de Hill):
C42H62O16
Peso molecular:
822.93
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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description
AldrichCPR
form
solid
SMILES string
[H][C@@]12C[C@](CC[C@@]1(CC[C@@]3(C2=CC([C@@]4([C@]5(CC[C@@H](C(C)([C@@]5(CC[C@@]34C)[H])C)O[C@H]6O[C@H](C(O)=O)[C@H]([C@@H]([C@H]6O[C@@H]7O[C@H](C(O)=O)[C@H]([C@@H]([C@H]7O)O)O)O)O)C)[H])=O)C)C)(C(O)=O)C
InChI
1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1
InChI key
LPLVUJXQOOQHMX-QWBHMCJMSA-N
General description
Glycyrrhizin is a plant glycoside derived from the liquorice (Glycyrrhiza glabra) plant root. It is a sweet-tasting molecule sweeter than sucrose (about 30-50 times), but it does not influence the glycemic index since it is not metabolized. It is often used as a natural emulsifier and gel-forming agent in foodstuffs,, beverages, and cosmetics.[1][2]
Other Notes
Please note that Sigma-Aldrich provides this product to early discovery researchers as part of a collection of unique chemicals. Sigma-Aldrich does not collect analytical data for this product. Buyer assumes responsibility to confirm product identity and/or purity. All sales are final.
NOTWITHSTANDING ANY CONTRARY PROVISION CONTAINED IN SIGMA-ALDRICH′S STANDARD TERMS AND CONDITIONS OF SALE OR AN AGREEMENT BETWEEN SIGMA-ALDRICH AND BUYER, SIGMA-ALDRICH SELLS THIS PRODUCT "AS-IS" AND MAKES NO REPRESENTATION OR WARRANTY WHATSOEVER WITH RESPECT TO THIS PRODUCT, INCLUDING ANY (A) WARRANTY OF MERCHANTABILITY, (B) WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE, OR (C) WARRANTY AGAINST INFRINGEMENT OF INTELLECTUAL PROPERTY RIGHTS OF A THIRD PARTY, WHETHER ARISING BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE.
NOTWITHSTANDING ANY CONTRARY PROVISION CONTAINED IN SIGMA-ALDRICH′S STANDARD TERMS AND CONDITIONS OF SALE OR AN AGREEMENT BETWEEN SIGMA-ALDRICH AND BUYER, SIGMA-ALDRICH SELLS THIS PRODUCT "AS-IS" AND MAKES NO REPRESENTATION OR WARRANTY WHATSOEVER WITH RESPECT TO THIS PRODUCT, INCLUDING ANY (A) WARRANTY OF MERCHANTABILITY, (B) WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE, OR (C) WARRANTY AGAINST INFRINGEMENT OF INTELLECTUAL PROPERTY RIGHTS OF A THIRD PARTY, WHETHER ARISING BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Introduction to the Chemistry of Food (2020)
Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?
Christian B and Gerard V
Pharmacology & Therapeutics, 214, 107618-107618 (2020)
Carina Dargel et al.
Biophysical journal, 118(10), 2411-2425 (2020-04-26)
In this study, we investigated the conversion of lipid bicelles into vesicles in the case of a system composed of the phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and the saponin glycyrrhizin in the presence of sucrose. Glycyrrhizin is a biosurfactant present in the
Christian Bailly et al.
Pharmacology & therapeutics, 214, 107618-107618 (2020-06-28)
Safe and efficient drugs to combat the current COVID-19 pandemic are urgently needed. In this context, we have analyzed the anti-coronavirus potential of the natural product glycyrrhizic acid (GLR), a drug used to treat liver diseases (including viral hepatitis) and
Noha M Shafik et al.
Archives of biochemistry and biophysics, 675, 108095-108095 (2019-09-03)
Rheumatoid arthritis (RA) is a systemic chronic autoimmune disease manifested by joint destruction and deformity, hence decreasing patient's life quality. The aim of the present work is to explore the mechanistic effects of glycyrrhizin (GL)and/or platelet rich plasma (PRP) treatment
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Can this product be given intraperitoneally to mice ? What does this compound dissolve in?
1 answer-
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Dear Representative How should I reserve Glycyrrhizin ? What is the appropriate temperature? Is there a data-sheet somewhere?
1 answer-
The storage information can be found in section 7 of the product's SDS. In this case, it can be stored at room temperature (as the SDS does not specify refrigerated or frozen temperature). Keep the container tightly closed in a dry and well-ventilated place. Please review the SDS for more safety and storage information.
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