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488577

Sigma-Aldrich

Cholesterol-2,2,3,4,4,6-d6

97 atom % D, 98% (CP)

Sinónimos:

3β-Hydroxy-5-cholestene-2,2,3,4,4,5-d6, 5-Cholesten-3β-ol-2,2,3,4,4,5-d6, Deuterated cholesterol

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About This Item

Fórmula empírica (notación de Hill):
C27D6H40O
Número de CAS:
92543-08-3
Peso molecular:
392.69
MDL number:
MFCD00209699
UNSPSC Code:
12352211
PubChem Substance ID:
24872407
NACRES:
NA.12

isotopic purity

97 atom % D

assay

98% (CP)

optical activity

[α]20/D -40°, c = 2 in chloroform

technique(s)

mass spectrometry (MS): suitable

bp

360 °C (lit.)

mp

147-149 °C (lit.)

density

1.088 g/mL at 25 °C

mass shift

M+6

storage temp.

−20°C

SMILES string

[2H]C1=C2C([2H])([2H])[C@@]([2H])(O)C([2H])([2H])C[C@]2(C)[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3C1)[C@H](C)CCCC(C)C

InChI

1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1/i9D,13D2,17D2,21D

InChI key

HVYWMOMLDIMFJA-HHPLMCQASA-N

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Yedida Y Bogachkov et al.
American journal of physiology. Cell physiology, 318(4), C762-C776 (2020-01-30)
Hypercholesterolemia is a major risk factor for adverse cardiovascular outcomes, but its effect on angiogenesis and wound healing is not well understood. In this study, using a combination of mass spectrometry and laurdan two-photon imaging, we show that elevated levels
Xianlin Han et al.
PloS one, 6(7), e21643-e21643 (2011-07-23)
The development of plasma biomarkers could facilitate early detection, risk assessment and therapeutic monitoring in Alzheimer's disease (AD). Alterations in ceramides and sphingomyelins have been postulated to play a role in amyloidogensis and inflammatory stress related neuronal apoptosis; however few
Vijayendran Raghavendran et al.
Biotechnology for biofuels, 13, 104-104 (2020-06-12)
Industrial biotechnology will play an increasing role in creating a more sustainable global economy. For conventional aerobic bioprocesses supplying O2 can account for 15% of total production costs. Microbubbles (MBs) are micron-sized bubbles that are widely used in industry and
Alice Passoni et al.
ACS chemical neuroscience, 11(3), 367-372 (2019-12-21)
The current pharmacological treatment of Huntington's disease (HD) is palliative, and therapies to restore functions in patients are needed. One of the pathways affected in HD involves brain cholesterol (Chol) synthesis, which is essential for optimal synaptic transmission. Recently, it
Yasuyo Okada et al.
Carbohydrate research, 455, 54-61 (2017-11-25)
We aimed to investigate whether 6-O-α-maltosyl-β-cyclodextrin (Mal-βCD) is incorporated into cells and lysosomes during the release of unesterified cholesterol in Npc1-deficient Chinese hamster ovary (CHO) cells (Npc1 KO cells) and CHO-JP17 cells (JP17 cells). Internalization of Mal-βCD in cells and lysosomes and
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