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Key Documents

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388513

Sigma-Aldrich

5,8-Dihydroxy-1,4-naphthoquinone

technical grade

Sinónimos:

Naphthazarin

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About This Item

Fórmula empírica (notación de Hill):
C10H6O4
Número de CAS:
475-38-7
Peso molecular:
190.15
Beilstein/REAXYS Number:
880561
EC Number:
207-495-4
MDL number:
MFCD00001685
UNSPSC Code:
12352103
PubChem Substance ID:
24864236
NACRES:
NA.23

grade

technical grade

mp

220-230 °C (lit.)

SMILES string

Oc1ccc(O)c2C(=O)C=CC(=O)c12

InChI

1S/C10H6O4/c11-5-1-2-6(12)10-8(14)4-3-7(13)9(5)10/h1-4,11-12H

InChI key

RQNVIKXOOKXAJQ-UHFFFAOYSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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BUTYL GALLATE AldrichCPR

S764868

BUTYL GALLATE

2,3-Dibromo-1,4-naphthoquinone 97%

Sigma-Aldrich

523429

2,3-Dibromo-1,4-naphthoquinone

Régis Millet et al.
Journal of medicinal chemistry, 48(22), 7024-7039 (2005-10-28)
The human selenoprotein thioredoxin reductase is involved in antioxidant defense and DNA synthesis. As increased thioredoxin reductase levels are associated with drug sensitivity to cisplatin and drug resistance in tumor cells, this enzyme represents a promising target for the development
Brígida R Pinho et al.
PloS one, 6(8), e24098-e24098 (2011-09-03)
The search of new anti-inflammatory drugs has been a current preoccupation, due to the need of effective drugs, with less adverse reactions than those used nowadays. Several naphthoquinones (plumbagin, naphthazarin, juglone, menadione, diosquinone and 1,4-naphthoquinone), plus p-hydroquinone and p-benzoquinone were
Vishnu K Tandon et al.
Bioorganic & medicinal chemistry letters, 15(13), 3288-3291 (2005-05-26)
A series of (1,4)-naphthoquinono [3,2-c]-1H-pyrazoles and their (1,4)-naphthohydroquinone derivatives 2-7 were synthesized and evaluated for antifungal, antibacterial, and anticancer activities. The structure-activity relationship of these compounds was studied and the results show that the compound 2b exhibited in vitro antifungal
Angela N Kuntz et al.
PLoS medicine, 4(6), e206-e206 (2007-06-21)
Schistosomiasis--infection with helminth parasites in the genus Schistosoma, including S. mansoni--is a widespread, devastating tropical disease affecting more than 200 million people. No vaccine is available, and praziquantel, the only drug extensively utilized, is currently administered more than 100 million
Eiríkur Stephensen et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 133(3), 435-442 (2002-10-16)
In fish, as in other aerobic organisms, glutathione and glutathione-related enzymes are important components in the defences against oxidative stress. To study if hepatic glutathione levels and/or activities of glutathione-related enzymes can act as indicators of oxidative stress in fish
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