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Merck

275352

Sigma-Aldrich

2-Hydroxy-5-nitrobenzaldehyde

98%

Sinónimos:

5-Nitrosalicylaldehyde

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About This Item

Fórmula lineal:
HOC6H3(NO2)CHO
Número de CAS:
Peso molecular:
167.12
Beilstein/REAXYS Number:
512565
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

98%

mp

125-128 °C (lit.)

SMILES string

[H]C(=O)c1cc(ccc1O)[N+]([O-])=O

InChI

1S/C7H5NO4/c9-4-5-3-6(8(11)12)1-2-7(5)10/h1-4,10H

InChI key

IHFRMUGEILMHNU-UHFFFAOYSA-N

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General description

2-Hydroxy-5-nitrobenzaldehyde is a nitroaromatic compound used to prepare Schiff base ligands.

The interaction of 2-hydroxy-5-nitrobenzaldehyde and chlorogenic acid (CHL) with the components of the rat hepatic glucose 6-phosphatase system was studied.

Physical properties

Free of 3-nitro isomer

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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M A Pajares et al.
The Journal of biological chemistry, 264(12), 6804-6809 (1989-04-25)
The 11-cis-retinal binding site of rhodopsin is of great interest because it is buried in the membrane but yet must provide an environment for charged amino acids. In addition, the active-site lysine residue must be able to engage in rapid
Qing-Bin Li et al.
Acta chimica Slovenica, 64(2), 500-505 (2017-06-18)
Two mononuclear Schiff base manganese(III) complexes, [MnL(N3)(OH2)]·CH3OH (1) and [MnL(NCS)(OH2)] · H2O (2), where L is the dianionic form of N,N'-bis(5-nitrosalicylidene)ethane-1,2-diamine, have been prepared and characterized by elemental analysis, IR and UV-Vis spectroscopy and single crystal X-ray diffraction. The Mn
Synthesis, spectroscopic characterization and antimicrobial activity of mono-, bi-and tri-nuclear metal complexes of a new Schiff base ligand
Shebl M,et al.
Journal of Molecular Structure, 980, 39-50 (2010)
Anke Rüttger et al.
BioTechniques, 41(4), 469-473 (2006-10-31)
A method is described allowing the selective determination of four cathepsins (B, H, K, and L) in live cells. Adherently growing cells are incubated with partially selective substrates for each cathepsin (peptidic derivatives of 4-methoxy-beta-naphthylamine) in microtiter plates together with
W J Arion et al.
Archives of biochemistry and biophysics, 339(2), 315-322 (1997-03-15)
We have studied the interactions of chlorogenic acid (CHL) and 2-hydroxy-5-nitrobenzaldehyde (HNB) with the components of the rat hepatic glucose 6-phosphatase (Glc-6-Pase) system. CHL and HNB are competitive inhibitors of glucose 6-phosphate (Glc-6-P) hydrolysis in intact microsomes with Ki values

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