This product has not been tested specifically for liposomal delivery systems. As such, we would refer to the academic literature to see if similar experiments utilizing thymoquinone have successfully been loaded into liposomes.
274666
Thymoquinone
≥98%
Sinónimos:
2-Isopropyl-5-methyl-1,4-benzoquinone
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About This Item
Fórmula empírica (notación de Hill):
C10H12O2
Número de CAS:
Peso molecular:
164.20
Número CE:
Número MDL:
Código UNSPSC:
12171500
ID de la sustancia en PubChem:
NACRES:
NA.47
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
Nivel de calidad
Ensayo
≥98%
Formulario
solid
técnicas
titration: suitable
color
yellow
bp
230-232 °C (lit.)
mp
45-47 °C (lit.)
aplicaciones
diagnostic assay manufacturing
hematology
histology
temp. de almacenamiento
room temp
cadena SMILES
CC(C)C1=CC(=O)C(C)=CC1=O
InChI
1S/C10H12O2/c1-6(2)8-5-9(11)7(3)4-10(8)12/h4-6H,1-3H3
Clave InChI
KEQHJBNSCLWCAE-UHFFFAOYSA-N
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Descripción general
Thymoquinone (TQ), also known as 2-isopropyl-5-methyl-1, 4-benzoquinone, is present in a crystalline triclinic form. It is the bioactive constituent of the volatile oil of black seed. TQ exhibits anti-inflammatory, antioxidant and anti-neoplastic effects both in vitro and in vivo.[1]
Aplicación
Thymoquinone has been used as an inhibitor of Escherichia coli ATP synthase and cell growth. It is also used as a drug against lower limb ischemia-reperfusion injury of the sciatic nerve and femoral muscle.[2]
Thymoquinone is employed in preclinical studies as a neuroprotective and anticonvulsant agent.
[2]
Thymoquinone is employed in preclinical studies as a neuroprotective and anticonvulsant agent.
[2]
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Órganos de actuación
Respiratory system
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
219.2 °F - closed cup
Punto de inflamabilidad (°C)
104 °C - closed cup
Equipo de protección personal
dust mask type N95 (US), Eyeshields, Gloves
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Certificados de análisis (COA)
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Los clientes también vieron
Thymoquinone: A promising anti-cancer drug from natural sources
Gali-Muhtasib H
The International Journal of Biochemistry & Cell Biology, 38, 1249-1253 (2006)
Hala Gali-Muhtasib et al.
The international journal of biochemistry & cell biology, 38(8), 1249-1253 (2005-11-30)
There has been growing interest in naturally occurring compounds with anti-cancer potential. Black seed is one of the most extensively studied plants. This annual herb grows in countries bordering the Mediterranean Sea and India. Thymoquinone (TQ) is the bioactive constituent
Sanjar Alam et al.
International journal of nanomedicine, 7, 5705-5718 (2012-11-28)
Chitosan (CS) nanoparticles of thymoquinone (TQ) were prepared by the ionic gelation method and are characterized on the basis of surface morphology, in vitro or ex vivo release, dynamic light scattering, and X-ray diffractometry (XRD) studies. Dynamic laser light scattering
Chern Chiuh Woo et al.
Biochemical pharmacology, 83(4), 443-451 (2011-10-19)
Thymoquinone is an active ingredient isolated from Nigella sativa and has been investigated for its anti-oxidant, anti-inflammatory and anticancer activities in both in vitro and in vivo models since its first extraction in 1960s. Its anti-oxidant/anti-inflammatory effect has been reported
Thymoquinone Inhibits Escherichia coli ATP Synthase and Cell Growth
Ahmad Z
PLoS ONE, 10 (2015)
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Can this substance be used for loading into liposomes?
1 answer-
Helpful?
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Hello I've bought 1 gram of Thymoquinone (product number: 274666) and I wanna use this in different concenteration for MTT assay. Could you please tell me that in which solvent I should dissolve the powder and How can I dillute it with PBS?
1 answer-
The solubility of this product is not determined. For analytical purposes, the material is heated to form a liquid and is tested in the neat form. Various sources indicate that this compound is soluble in DMSO, DMF, and Ethanol. Please see the link below to review a publication that indicates stock solutions may then be further diluted in phosphate buffer:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270770/Helpful?
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