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Key Documents

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211281

Sigma-Aldrich

9-Phenanthrol

technical grade

Sinónimos:

9-Hydroxyphenanthrene

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About This Item

Fórmula empírica (notación de Hill):
C14H10O
Número de CAS:
484-17-3
Peso molecular:
194.23
EC Number:
207-602-4
MDL number:
MFCD00082298
UNSPSC Code:
12352100
PubChem Substance ID:
24852666
NACRES:
NA.22

grade

technical grade

mp

139-143 °C (lit.)

SMILES string

Oc1cc2ccccc2c3ccccc13

InChI

1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H

InChI key

DZKIUEHLEXLYKM-UHFFFAOYSA-N

Application

9-Phenanthrol was used to investigate C K-edge and O K-edge near-edge X-ray absorption fine structure (NEXAFS) spectra of single-wall carbon nanotubes.

Biochem/physiol Actions

9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Ana Mrejeru et al.
The Journal of physiology, 589(Pt 10), 2497-2514 (2011-04-14)
Nigral dopamine neurons are transiently activated by high frequency glutamatergic inputs relaying reward-predicting sensory information. The tonic firing pattern of dopamine cells responds to these inputs with a transient burst of spikes that requires NMDA receptors. Here, we show that
T Grand et al.
British journal of pharmacology, 153(8), 1697-1705 (2008-02-26)
TRPM4 and TRPM5 are calcium-activated non-selective cation channels with almost identical characteristics. TRPM4 is detected in several tissues including heart, kidney, brainstem, cerebral artery and immune system whereas TRPM5 expression is more restricted. Determination of their roles in physiological processes
Eric C Lin et al.
Frontiers in cellular neuroscience, 11, 182-182 (2017-07-18)
Temporal lobe epilepsy is characterized by recurrent seizures in one or both temporal lobes of the brain; some
Stefano Masoli et al.
Communications biology, 3(1), 222-222 (2020-05-10)
The cerebellar granule cells (GrCs) are classically described as a homogeneous neuronal population discharging regularly without adaptation. We show that GrCs in fact generate diverse response patterns to current injection and synaptic activation, ranging from adaptation to acceleration of firing.
Amy C Smith et al.
American journal of physiology. Cell physiology, 304(5), C467-C477 (2013-01-11)
Members of the transient receptor potential (TRP) channel superfamily, including the Ca(2+)-activated monovalent cation-selective TRP melastatin 4 (TRPM4) channel, have been recently identified in the urinary bladder. However, their expression and function at the level of detrusor smooth muscle (DSM)
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