157864

1-Acetylimidazole

98%

• Sinónimos: 1-(1H-Imidazol-1-yl)ethan-1-one, 1-(1H-Imidazol-1-yl)ethanone, 1-Acetyl-1H-imidazole, N-Acetylimidazole
• Fórmula empírica (notación de Hill): C₅H₆N₂O
• Número de CAS: 2466-76-4
• Peso molecular: 110.11
• Beilstein/REAXYS Number: 108425
• EC Number: 219-577-7
• MDL number: MFCD00005287
• UNSPSC Code: 12352005
• PubChem Substance ID: 24849704
• NACRES: NA.22

Propiedades

• Quality Level: 200
• assay: 98%
• form: solid
• mp: 99-105 °C (lit.)
• solubility: water: soluble 50 mg/mL, clear, colorless
• storage temp.: 2-8°C
• SMILES string: CC(=O)n1ccnc1
• InChI: 1S/C5H6N2O/c1-5(8)7-3-2-6-4-7/h2-4H,1H3
• InChI key: VIHYIVKEECZGOU-UHFFFAOYSA-N

Descripción

General description

Rate of solvolysis of 1-acetylimidazole in acid solutions was evaluated. Reaction of 1-acetylimidazole with orthophosphate and adenosine-5′-phosphate has been reported.

Application

1-Acetylimidazole was used as acetylation reagent for amino groups. It was also employed for acetylation of histones.

Relatively specific reagent for tyrosyl residue acetylation. Reagent used in the synthesis of annulated imidazole derivatives.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)