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Supelco

Sulfamethoxypyridazine

VETRANAL®, analytical standard

Synonym(s):

N1-(6-Methoxypyridazin-3-yl)sulfanilamide

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About This Item

Empirical Formula (Hill Notation):
C11H12N4O3S
CAS Number:
Molecular Weight:
280.30
Beilstein:
277076
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1

InChI

1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)

InChI key

VLYWMPOKSSWJAL-UHFFFAOYSA-N

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General description

Sulfamethoxypyridazine is a sulfonamide antibiotic mainly used to prevent infections as well as conditions such as coccidiosis, diarrhea and gastroenteritis.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfamethoxypyridazine may be used as a reference standard for the determination of sulfamethoxypyridazine in pharmaceutical formulations by liquid chromatography method.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Quantum chemical investigation on photodegradation mechanisms of sulfamethoxypyridazine with dissolved inorganic matter and hydroxyl radical.
Shah S and Hao C
Journal of environmental sciences (China), 57, 85-92 (2017)
Sai Ye et al.
Journal of separation science, 30(15), 2360-2369 (2007-09-01)
This paper describes a rapid method for the determination of 14 kinds of sulfonamides (SAs) in wastewater using SPE, and LC-MS/MS with positive ESI (ESI(+)) and selected reaction monitoring (SRM) mode. The SPE was performed on an Oasis hydrophilic-lipophilic-balanced (HLB)
J B Escalera et al.
The Journal of pharmacy and pharmacology, 46(3), 172-176 (1994-03-01)
An approach to reproduce the solubility profile of a drug in several solvent mixtures showing two solubility maxima is proposed in this work. The solubility of sulphamethoxypyridazine was determined at 25 degrees C in several mixtures of varying polarity (hexane:ethyl
Leticia López-Martínez et al.
Journal of pharmaceutical and biomedical analysis, 30(1), 77-85 (2002-08-02)
The bivariate calibration algorithm was applied to the spectrophotometric simultaneous determination of trimethoprim (TMP), sulfamethoxazole (SMX) or sulphamethoxypyridazine (SMP) binary mixtures in pharmaceutical and veterinary products. The results obtained were compared with those from derivative spectrophotometry. The statistical evaluation of
Ivan Yu Sakharov et al.
Journal of agricultural and food chemistry, 58(6), 3284-3289 (2010-02-24)
An indirect competitive chemiluminescent enzyme-linked immunosorbent assay (CL-ELISA) of sulfamethoxypyridazine (SMP) was developed. The conjugates of streptavidin with cationic horseradish peroxidase (HRP) and anionic soybean peroxidase (SbP) were used in CL-ELISA for the detection of biotinylated anti-SMP antibodies. For streptavidin-HRP

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