23955

Chlorodipyrrolidinocarbenium hexafluorophosphate

≥97.5% (CHN)

• Synonym(s): N,N,N′,N′-Bis(tetramethylene)chloroformamidinium hexafluorophosphate, Chloro-N,N,N′,N′-bis(tetramethylene)formamidinium hexafluorophosphate, PyClU
• Linear Formula: C₉H₁₆N₂Cl · PF₆
• CAS Number: 135540-11-3
• Molecular Weight: 332.65
• Beilstein: 7898575
• MDL number: MFCD00191333
• UNSPSC Code: 12352101
• PubChem Substance ID: 57648043
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥97.5% (CHN)
• form: solid
• reaction suitability: reaction type: Coupling Reactions
• mp: 153-156 °C
• application(s): peptide synthesis
• functional group: chloro
• storage temp.: 2-8°C
• SMILES string: F[P-](F)(F)(F)(F)F.Cl\C(N1CCCC1)=[N+]2/CCCC2
• InChI: 1S/C9H16ClN2.F6P/c10-9(11-5-1-2-6-11)12-7-3-4-8-12;1-7(2,3,4,5)6/h1-8H2;/q+1;-1
• InChI key: NHEGCUSBUWGOQM-UHFFFAOYSA-N

Description

Application

Reactant for:
Enantioselective desymmetrization of meso-asiridines
Peptide coupling
Reagent for:
Heterocyclization of chloroformamidinium salts
Oxidative insertion for palladium and nickel catalyst synthesis

Other Notes

Crystalline and non-hygroscopic peptide coupling reagent, especially for N-methyl amino acids

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves