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Key Documents

V7127

Sigma-Aldrich

D-Val-Leu-Lys p-nitroanilide dihydrochloride

plasmin substrate, chromogenic, ≥98% (HPLC), powder

Synonyme(s) :

D-Val-Leu-Lys p-nitroanilide

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About This Item

Formule empirique (notation de Hill):
C23H38N6O5 · 2HCl
Poids moléculaire :
551.51
Code UNSPSC :
12352204
ID de substance PubChem :
24900765
Nomenclature NACRES :
NA.32

product name

D-Val-Leu-Lys p-nitroanilide dihydrochloride, plasmin substrate

Niveau de qualité

200

Pureté

≥98% (HPLC)

Forme

powder

Solubilité

water: 50 mg/mL, clear, light yellow

Température de stockage

−20°C

InChI

1S/C23H38N6O5.ClH/c1-14(2)13-19(28-23(32)20(25)15(3)4)22(31)27-18(7-5-6-12-24)21(30)26-16-8-10-17(11-9-16)29(33)34;/h8-11,14-15,18-20H,5-7,12-13,24-25H2,1-4H3,(H,26,30)(H,27,31)(H,28,32);1H

Clé InChI

ITWYYDDNWFVYSU-UHFFFAOYSA-N

Application

D-Val-Leu-Lys p-nitroanilide dihydrochloride has been used:
  • as substrate to measure the activity of plasminogen activator by a chromogenic assay
  • as a p-nitroanilide (pNA) substrate to measure the specific activities of serine protease isoforms in Gloydius intermedius venom
  • as a substrate in total plasmin assay using milk/cream samples

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Warning

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Zhang-Min Yang et al.
Journal of proteomics, 164, 19-32 (2017-05-31)
Nine distinct venom serine proteases (vSPs) of Gloydius intermedius were studied by transcriptomic, sub-proteomic and phylogenetic analyses. Their complete amino acid sequences were deduced after Expression Sequence Tag (EST) analyses followed by cDNA cloning and sequencing. These vSPs appear to
Ezio Fasoli et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 930, 13-21 (2013-05-25)
Despite membrane-based separations offering superior alternative to packed bed chromatographic processes, there has been a substantial lacuna in their actual application to separation processes. One of the major reasons behind this is the lack of availability of appropriately modified or
S Vijayakumar et al.
Journal of dairy science, 98(10), 6678-6691 (2015-08-04)
The shelf life of pasteurized milk is limited by heat-stable proteases, which cause gelation and bitter taste upon extended storage of milk. Ultra-high temperature processing inactivates proteases but detrimentally affects milk's sensory quality. An adjunct to pasteurization is desired to
Role of lysine binding regions in the kinetic properties of human plasmin.
J P Morris et al.
Biochemistry, 20(17), 4811-4816 (1981-08-18)
Warren B Nothnick et al.
PloS one, 9(6), e100336-e100336 (2014-06-18)
Endometriosis is defined as the growth of endometrial glandular and stromal components in ectopic locations and affects as many as 10% of all women of reproductive age. Despite its high prevalence, the pathogenesis of endometriosis remains poorly understood. MicroRNAs, small
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