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RAB0429

Sigma-Aldrich

Human PAI-1 ELISA Kit

for serum, plasma, cell culture supernatant.

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About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.32

Espèces réactives

human

Conditionnement

kit of 96 wells (12 strips x 8 wells)

Technique(s)

ELISA: suitable
capture ELISA: suitable

Entrée

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 35 pg/mL
standard curve range: 0.102-25 ng/mL

Méthode de détection

colorimetric

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

human ... SERPINE1(5054)

Description générale

The Human PAI-1 (plasminogen activator inhibitor-1) ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human PAI-1 in serum, plasma, cell culture supernatants. PAI-1 is 45kDa serine proteinase inhibitor. It inhibits plasmogen activator and affects the fibrinolytic process, as a result of which it leads to thrombosis. Reduced fibrinolysis is observed in ischemic heart disease. While elevated PAI-1 levels are noticed in myocardial infarction. PAI-1 is associated with various physiological processes including wound healing, sepsis, insulin resistance, obesity, atherosclerosis, tumor angiogenesis, bone remodeling, asthma, rheumatoid arthritis, glomerulonephritis and chronic stress.

Immunogène

Recombinant Human PAI-I

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Autres remarques

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Description
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  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)FDS
  • RABSTOP3ELISA Stop Solution (Item I)FDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)FDS
  • RABWASH420X Wash Buffer (Item B)FDS

Pictogrammes

Corrosion
GHS05

Mention d'avertissement

Warning

Mentions de danger

H290

Conseils de prudence

P234 - P390

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Jessica Perugini et al.
Scientific reports, 12(1), 8331-8331 (2022-05-19)
To establish whether obesity involves activation of endogenous ciliary neurotrophic factor (CNTF) signalling, we evaluated its plasma levels in patients with obesity and correlated its values with the major clinical and haematological indices of obesity, insulin resistance and systemic inflammation.
Brain Edema XI: Proceedings of the 11th International Symposium, 277-277 (1999)
María Paniagua-Sancho et al.
American journal of nephrology, 52(9), 714-724 (2021-09-15)
Acute kidney injury (AKI) is a threatening, multiaetiological syndrome encompassing a variety of forms and damage patterns. AKI lacks sufficiently specific diagnostic tools to evaluate the distinct combination of pathophysiological events underlying each case, which limits personalized and optimized handling.
Pleiotropic functions of plasminogen activator inhibitor-1
Lijnen, HR
Journal of Thrombosis and Haemostasis, 3(1), 35-45 (2005)
Gui Yang et al.
The Journal of allergy and clinical immunology, 133(6), 1702-1708 (2014-04-05)
The functions of regulatory T (Treg) cells are important in immunity, and the regulatory mechanisms of Treg cell activities are not fully understood yet. We sought to investigate the role of insulin-like growth factor (IGF) 2 in the upregulation of

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