R1512

Rétinyl-palmitate

potency: ≥1,700,000 USP units per g

• Synonyme(s) : Palmitate de vitamine A, palmitate de tout−trans−rétinol
• Formule empirique (notation de Hill): C₃₆H₆₀O₂
• Numéro CAS: 79-81-2
• Poids moléculaire : 524.86
• Numéro Beilstein : 1917366
• Numéro CE : 201-228-5
• Numéro MDL: MFCD00019414
• Code UNSPSC : 12352205
• ID de substance PubChem : 24899347
• Nomenclature NACRES : NA.79

Propriétés

• Source biologique: synthetic (organic)
• Forme: solid or viscous liquid
• Puissance: ≥1,700,000 USP units per g
• Ne contient pas: antioxidant
• Couleur: yellow to yellow-green
• Pf: 26 °C
• Température de stockage: 2-8°C
• Chaîne SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1
• InChI: 1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+
• Clé InChI: VYGQUTWHTHXGQB-FFHKNEKCSA-N

Description

Description générale

Retinyl palmitate or vitamin A palmitate is a retinoid, which is an acid form of vitamin A. Retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinyl palmitate is a major storage form of vitamin A found in epidermis. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed.

Application

Retinyl palmitate has been used as a standard in high performance liquid chromatography (HPLC). It has also been used to study its effect on brain regeneration in larval Xenopus laevis.

Actions biochimiques/physiologiques

Retinyl palmitate is widely used in pharmaceutical applications. It is also extensively used in cosmetic formulations due to its beneficial effects on the appearance of skin and anti-oxidant properties. Retinyl palmitate acts as a teratogen and affect vertebrate embryogenesis and regeneration. It is added as a source of vitamin A in low fat and skim milks. Retinyl palmitate acts as a chemopreventive or antineoplastic agent.

Revue : Métabolisme de la vitamine A.

Conditionnement

Sealed ampule.

Forme physique

oil or solid

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H360D,H412
• Conseils de prudence: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Aquatic Chronic 3 - Repr. 1B
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): No data available
• Point d'éclair (°C): No data available
• Équipement de protection individuelle: Eyeshields, Gloves, type ABEK (EN14387) respirator filter