M7397

L-(−)-Malic acid

suitable for cell culture, BioReagent, suitable for insect cell culture

• Synonyme(s) : (S)-(−)-2-Hydroxysuccinic acid, L-Hydroxybutanedioic acid
• Formule linéaire : HO₂CCH₂CH(OH)CO₂H
• Numéro CAS: 97-67-6
• Poids moléculaire : 134.09
• Numéro Beilstein : 1723541
• Numéro CE : 202-601-5
• Numéro MDL: MFCD00064213
• Code UNSPSC : 12352205
• ID de substance PubChem : 24897161
• Nomenclature NACRES : NA.75

Propriétés

• Source biologique: microbial
• Gamme de produits: BioReagent
• Pureté: ≥95% (titration)
• Forme: powder
• Technique(s): cell culture | insect: suitable; cell culture | mammalian: suitable
• Pf: 101-103 °C (lit.)
• Solubilité: water: 100 mg/mL, clear to slightly hazy, colorless
• Chaîne SMILES: O[C@@H](CC(O)=O)C(O)=O
• InChI: 1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
• Clé InChI: BJEPYKJPYRNKOW-REOHCLBHSA-N

Description

Description générale

Malic acid is used as a component of insect tissue culture. It is also useful as an acidulant in soft drinks, jams, fruit and vegetable juices.

Application

Malic acid has been used:

• to induce basal respiration in mitochondrial cell culture
• to measure the mitochondrial ETC (electron transport chain) activity
• as a component of mitochondrial substrate stock

Actions biochimiques/physiologiques

Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319
• Conseils de prudence: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves