E6511

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate

BioReagent, suitable for cell culture, 98.5-102.0%

• Synonyme(s) : EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate dihydrate
• Formule linéaire : (NaOOCCH₂)₂NCH₂CH₂N(CH₂COONa)₂ · 2H₂O
• Numéro CAS: 10378-23-1
• Poids moléculaire : 416.20
• Beilstein: 3861753
• Numéro CE : 200-573-9
• Numéro MDL: MFCD00150026
• Code UNSPSC : 12352204
• ID de substance PubChem : 24894629
• Nomenclature NACRES : NA.75

Propriétés

• Gamme de produits: BioReagent
• Niveau de qualité: 200
• Essai: 98.5-102.0%
• Forme: powder
• Technique(s): cell culture | mammalian: suitable
• Plage de pH: 11.0-11.7
• Solubilité: H₂O: 160 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: room temp
• Chaîne SMILES: O.O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.4Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;2*1H2/q;4*+1;;/p-4
• Clé InChI: KSYNLCYTMRMCGG-UHFFFAOYSA-J

Description

Description générale

Ethylenediaminetetraacetic acid (EDTA) is a chelator of metal ions.[1] It is a substituted diamine, which has antibacterial activity. EDTA removes the undesirable effects of ferric, cupric and manganic ions in bleaching. It prevents cellular division, chlorophyll synthesis and algal biomass production.[2] EDTA is an inhibitor of metalloprotease.[1] It has anticoagulant property.[3]

Application

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate has been used:

• as a chelating agent to isolate human endometrial stem cell/stromal cells (hEnSCs) from menstrual blood[4]
• as a chelator in animal and testicular cell isolation[5]
• as a chelator for the culture of neural stem cells[6]

Actions biochimiques/physiologiques

Ethylenediaminetetraacetic acid (EDTA) is used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS05,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H302 + H332,H318,H373
• Conseils de prudence: P260 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Classification des risques: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2
• Organes cibles: Respiratory Tract
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves